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Browsing Department of Biostatistics by Title

OpenBU

Browsing Department of Biostatistics by Title

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  • Porter, Stacy A.; Massaro, Joseph M.; Hoffmann, Udo; Vasan, Ramachandran S.; O'Donnel, Christopher J.; Fox, Caroline S. (American Diabetes Association, 2009-3-5)
    OBJECTIVE: Obesity is associated with increased metabolic and cardiovascular risk. The ectopic fat hypothesis suggests that subcutaneous fat may be protective, but this theory has yet to be fully explored. RESEARCH DESIGN ...
  • Losina, Elena; Bassett, Ingrid V.; Giddy, Janet; Chetty, Senica; Regan, Susan; Walensky, Rochelle P.; Ross, Douglas; Scott, Callie A.; Uhler, Lauren M.; Katz, Jeffrey N.; Holst, Helga; Freedberg, Kenneth A. (Public Library of Science, 2010-3-4)
    BACKGROUND. Although loss to follow-up after antiretroviral therapy (ART) initiation is increasingly recognized, little is known about pre-treatment losses to care (PTLC) after an initial positive HIV test. Our objective ...
  • Rydzak, Chara E.; Cotich, Kara L.; Sax, Paul E.; Hsu, Heather E.; Wang, Bingxia; Losina, Elena; Freedberg, Kenneth A.; Weinstein, Milton C.; Goldie, Sue J. (Public Library of Science, 2010-9-9)
    BACKGROUND. Model-based analyses, conducted within a decision analytic framework, provide a systematic way to combine information about the natural history of disease and effectiveness of clinical management strategies ...
  • Vieira, Verónica M.; Hart, Jaime E.; Webster, Thomas F.; Weinberg, Janice; Puett, Robin; Laden, Francine; Costenbader, Karen H.; Karlson, Elizabeth W. (National Institute of Environmental Health Sciences, 2010-07)
    BACKGROUND. The etiology of rheumatoid arthritis (RA) remains largely unknown, although epidemiologic studies suggest genetic and environmental factors may play a role. Geographic variation in incident RA has been observed ...
  • Molenaar, Esther A.; Massaro, Joseph M.; Jacques, Paul F.; Pou, Karla M.; Ellison, R. Curtis; Hoffmann, Udo; Pencina, Karol; Shadwick, Steven D.; Vasan, Ramachandran S.; O'Donnell, Christopher J.; Fox, Caroline S. (American Diabetes Association, 2011-12-29)
    OBJECTIVE: The purpose of this study was to assess the relationship between lifestyle factors and abdominal subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) in a community-based setting. RESEARCH DESIGN ...
  • Lieb, Wolfgang; Pencina, Michael J.; Lanier, Katherine J.; Tofler, Geoffrey H.; Levy, Daniel; Fox, Caroline S.; Wang, Thomas J.; D'Agostino, Ralph B.; Vasan, Ramachandran S. (American Diabetes Association, 2011-12-29)
    OBJECTIVE: Parental obesity is a risk factor for offspring obesity. It is unclear whether parental obesity also confers risk for obesity-associated conditions (e.g., a proinflammatory or prothrombotic state) in the absence ...
  • Hatch, Elizabeth E; Nelson, Jessica W; Qureshi, M Mustafa; Weinberg, Janice; Moore, Lynn L; Singer, Martha; Webster, Thomas F (BioMed Central, 2008-6-3)
    BACKGROUND: Although diet and activity are key factors in the obesity epidemic, laboratory studies suggest that endocrine disrupting chemicals may also affect obesity. METHODS: We analyzed associations between six phthalate ...
  • Hivert, Marie-France; Manning, Alisa K.; McAteer, Jarred B.; Dupuis, Josée; Fox, Caroline S.; Cupples, L. Adrienne; Meigs, James B.; Florez, Jose C. (American Diabetes Association, 2011-12-29)
    OBJECTIVE: The RETN gene encodes the adipokine resistin. Associations of RETN with plasma resistin levels, type 2 diabetes, and related metabolic traits have been inconsistent. Using comprehensive linkage disequilibrium ...
  • Thwin, Soe Soe; Clough-Gorr, Kerri M; McCarty, Maribet C; Lash, Timothy L; Alford, Sharon H; Buist, Diana SM; Enger, Shelley M; Field, Terry S; Frost, Floyd; Wei, Feifei; Silliman, Rebecca A (BioMed Central, 2007-6-18)
    BACKGROUND: The choice between paper data collection methods and electronic data collection (EDC) methods has become a key question for clinical researchers. There remains a need to examine potential benefits, efficiencies, ...
  • Desikan, Rahul S.; Cabral, Howard J.; Hess, Christopher P.; Dillon, William P.; Glastonbury, Christine M.; Weiner, Michael W.; Schmansky, Nicholas J.; Greve, Douglas N.; Salat, David H.; Buckner, Randy L.; Fischl, Bruce (Oxford University Press, 2009-5-21)
    Mild cognitive impairment can represent a transitional state between normal ageing and Alzheimer's disease. Non-invasive diagnostic methods are needed to identify mild cognitive impairment individuals for early therapeutic ...
  • Sebastiani, Paola (2010-01-27)
    A program for analysis of differential gene expression data using Bayesian model averaging.
  • Ferrazzi, Fulvia; Sebastiani, Paola; Ramoni, Marco F; Bellazzi, Riccardo (BioMed Central, 2007-5-24)
    BACKGROUND. Reverse engineering cellular networks is currently one of the most challenging problems in systems biology. Dynamic Bayesian networks (DBNs) seem to be particularly suitable for inferring relationships between ...
  • Sebastiani, Paola; Abad-Grau, María M (BioMed Central, 2007-6-25)
    BACKGROUND: The maximum likelihood estimator of D' – a standard measure of linkage disequilibrium – is biased toward disequilibrium, and the bias is particularly evident in small samples and rare haplotypes. RESULTS: This ...
  • Sebastiani, Paola (2010-01-27)
    A program for learning Bayesian networks from data and reasoning using probabilistic inference.
  • Hunter, David J; LaValley, Michael; Li, Jiang; Bauer, Doug C; Nevitt, Michael; DeGroot, Jeroen; Poole, Robin; Eyre, David; Guermazi, Ali; Gale, Daniel; Totterman, Saara; Felson, David T (BioMed Central, 2008-8-29)
    INTRODUCTION. Our objective was to determine whether markers of bone resorption and formation could serve as markers for the presence of bone marrow lesions (BMLs). METHODS. We conducted an analysis of data from the Boston ...
  • Sebastiani, Paola (2010-01-27)
    Computer program for the analysis of temporal expression profiles of gene expression data
  • Fredman, Lisa; Doros, Gheorghe; Cauley, Jane A.; Hillier, Teresa A.; Hochberg, Marc C. (Oxford University Press, 2010-3-29)
    BACKGROUND Chronic stress may lead to health decline through metabolic syndrome. Thus, persons in stressful caregiving situations who also have more indicators of metabolic syndrome may experience more decline than other ...
  • Larson, Pamela S; Schlechter, Benjamin L; King, Chia-Lin; Yang, Qiong; Glass, Chelsea N; Mack, Charline; Pistey, Robert; de las Morenas, Antonio; Rosenberg, Carol L (BioMed Central, 2008-3-6)
    BACKGROUND. CDKN1C (also known as p57KIP2) is a cyclin-dependent kinase inhibitor previously implicated in several types of human cancer. Its family members (CDKN1A/p21CIP1 and B/p27KIP1) have been implicated in breast ...
  • Ozonoff, Al; Webster, Thomas; Vieira, Veronica; Weinberg, Janice; Ozonoff, David; Aschengrau, Ann (BioMed Central, 2005-9-15)
    BACKGROUND: A variety of statistical methods have been suggested to assess the degree and/or the location of spatial clustering of disease cases. However, there is relatively little in the literature devoted to comparison ...
  • Hivert, Marie-France; Manning, Alisa K.; McAteer, Jarred B.; Florez, Jose C.; Dupuis, Josée; Fox, Caroline S.; O'Donnell, Christopher J.; Cupples, L. Adrienne; Meigs, James B. (American Diabetes Association, 2011-12-29)
    OBJECTIVE: Variants in ADIPOQ have been inconsistently associated with adiponectin levels or diabetes. Using comprehensive linkage disequilibrium mapping, we genotyped single nucleotide polymorphisms (SNPs) in ADIPOQ to ...

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