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Browsing Department of Biostatistics by Title

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Browsing Department of Biostatistics by Title

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  • Reichmann, William M.; Losina, Elena; Seage, George R.; Arbelaez, Christian; Safren, Steven A.; Katz, Jeffrey N.; Hetland, Adam; Walensky, Rochelle P. (Public Library of Science, 2010-1-15)
    BACKGROUND. In the context of a randomized controlled trial (RCT) on HIV testing in the emergency department (ED) setting, we evaluated preferences for survey modality and data quality arising from each modality. METHODS. ...
  • Pani, Lydie N.; Korenda, Leslie; Meigs, James B.; Driver, Cynthia; Chamany, Shadi; Fox, Caroline S.; Sullivan, Lisa; D'Agostino, Ralph B.; Nathan, David M. (American Diabetes Association, 2011-12-29)
    OBJECTIVE: Although glycemic levels are known to rise with normal aging, the nondiabetic A1C range is not age specific. We examined whether A1C was associated with age in nondiabetic subjects and in subjects with normal ...
  • Ozonoff, Al; Jeffery, Caroline; Manjourides, Justin; White, Laura Forsberg; Pagano, Marcello (BioMed Central, 2007-11-27)
    BACKGROUND. Aggregation of spatial data is intended to protect privacy, but some effects of aggregation on spatial methods have not yet been quantified. METHODS. We generated 3,000 spatial data sets and evaluated power of ...
  • Meredith, Dennis S; Losina, Elena; Neumann, Gesa; Yoshioka, Hiroshi; Lang, Philipp K; Katz, Jeffrey N (BioMed Central, 2009-10-29)
    BACKGROUND: In this cross-sectional study, we conducted a comprehensive assessment of all articular elements that could be measured using knee MRI. We assessed the association of pathological change in multiple articular ...
  • Latourelle, Jeanne C; Dybdahl, Merete; Destefano, Anita L; Myers, Richard H; Lash, Timothy L (Dove Medical Press, 2010-8-9)
    PURPOSE: Estrogen exposure has been associated with the occurrence of Parkinson's disease (PD), as well as many other disorders, and yet the mechanisms underlying these relations are often unknown. While it is likely that ...
  • Reichmann, William M; Gagnon, David; Horsburgh, C Robert; Losina, Elena (BioMed Central, 2011-1-5)
    BACKGROUND: Previous studies have proposed a simple product-based estimator for calculating exposure-specific risks (ESR), but the methodology has not been rigorously evaluated. The goal of our study was to evaluate the ...
  • Spence, Lisa A; Aschengrau, Ann; Gallagher, Lisa E; Webster, Thomas F; Heeren, Timothy C; Ozonoff, David M (BioMed Central, 2008-6-2)
    BACKGROUND: From May 1968 through March 1980, vinyl-lined asbestos-cement (VL/AC) water distribution pipes were installed in New England to avoid taste and odor problems associated with asbestos-cement pipes. The vinyl ...
  • Laramie, Jason M; Wilk, Jemma B; Hunt, Steven C; Ellison, R Curtis; Chakravarti, Aravinda; Boerwinkle, Eric; Myers, Richard H (BioMed Central, 2006-3-1)
    BACKGROUND: Elevated resting heart rate has been shown in multiple studies to be a strong predictor of cardiovascular disease. Previous family studies have shown a significant heritable component to heart rate with several ...
  • Paulu, Christopher; Aschengrau, Ann; Ozonoff, David (National Institute of Environmental Health Sciences, 2002-05)
    Locating geographic hot spots of cancer may lead to new causal hypotheses and ultimately to new knowledge of cancer-causing factors. The Cape Cod region of Massachusetts has experienced elevated incidence of breast cancer ...
  • Hoffman, Kate; Webster, Thomas F.; Weisskopf, Marc G.; Weinberg, Janice; Vieira, Verónica M. (National Institute of Environmental Health Sciences, 2010-12)
    BACKGROUND. Polyfluoroalkyl chemicals (PFCs) have been widely used in consumer products. Exposures in the United States and in world populations are widespread. PFC exposures have been linked to various health impacts, and ...
  • Chasman, Daniel I.; Paré, Guillaume; Mora, Samia; Hopewell, Jemma C.; Peloso, Gina; Clarke, Robert; Cupples, L. Adrienne; Hamsten, Anders; Kathiresan, Sekar; Mälarstig, Anders; Ordovas, José M.; Ripatti, Samuli; Parker, Alex N.; Miletich, Joseph P.; Ridker, Paul M. (Public Library of Science, 2009-11-20)
    While conventional LDL-C, HDL-C, and triglyceride measurements reflect aggregate properties of plasma lipoprotein fractions, NMR-based measurements more accurately reflect lipoprotein particle concentrations according to ...
  • Larson, Martin G; Atwood, Larry D; Benjamin, Emelia J; Cupples, L Adrienne; D'Agostino, Ralph B; Fox, Caroline S; Govindaraju, Diddahally R; Guo, Chao-Yu; Heard-Costa, Nancy L; Hwang, Shih-Jen; Murabito, Joanne M; Newton-Cheh, Christopher; O'Donnell, Christopher J; Seshadri, Sudha; Vasan, Ramachandran S; Wang, Thomas J; Wolf, Philip A; Levy, Daniel (BioMed Central, 2007-9-19)
    BACKGROUND: Cardiovascular disease (CVD) and its most common manifestations – including coronary heart disease (CHD), stroke, heart failure (HF), and atrial fibrillation (AF) – are major causes of morbidity and mortality. ...
  • Cupples, L Adrienne; Arruda, Heather T; Benjamin, Emelia J; D'Agostino, Ralph B; Demissie, Serkalem; DeStefano, Anita L; Dupuis, Josée; Falls, Kathleen M; Fox, Caroline S; Gottlieb, Daniel J; Govindaraju, Diddahally R; Guo, Chao-Yu; Heard-Costa, Nancy L; Hwang, Shih-Jen; Kathiresan, Sekar; Kiel, Douglas P; Laramie, Jason M; Larson, Martin G; Levy, Daniel; Liu, Chun-Yu; Lunetta, Kathryn L; Mailman, Matthew D; Manning, Alisa K; Meigs, James B; Murabito, Joanne M; Newton-Cheh, Christopher; O'Connor, George T; O'Donnell, Christopher J; Pandey, Mona; Seshadri, Sudha; Vasan, Ramachandran S; Wang, Zhen Y; Wilk, Jemma B; Wolf, Philip A; Yang, Qiong; Atwood, Larry D (BioMed Central, 2007-9-19)
    BACKGROUND: The Framingham Heart Study (FHS), founded in 1948 to examine the epidemiology of cardiovascular disease, is among the most comprehensively characterized multi-generational studies in the world. Many collected ...
  • Yang, Qiong; Chazaro, Irmarie; Cui, Jing; Guo, Chao-Yu; Demissie, Serkalem; Larson, Martin; Atwood, Larry D; Cupples, L Adrienne; DeStefano, Anita L (BioMed Central, 2003-12-31)
    BACKGROUND. We explored three approaches to heritability and linkage analyses of longitudinal total cholesterol levels (CHOL) in the Genetic Analysis Workshop 13 simulated data without knowing the answers. The first two ...
  • Bailey-Wilson, Joan E; Almasy, Laura; de Andrade, Mariza; Bailey, Julia; Bickeböller, Heike; Cordell, Heather J; Daw, E Warwick; Goldin, Lynn; Goode, Ellen L; Gray-McGuire, Courtney; Hening, Wayne; Jarvik, Gail; Maher, Brion S; Mendell, Nancy; Paterson, Andrew D; Rice, John; Satten, Glen; Suarez, Brian; Vieland, Veronica; Wilcox, Marsha; Zhang, Heping; Ziegler, Andreas; MacCluer, Jean W (BioMed Central, 2005-12-30)
  • Cordell, Heather J; de Andrade, Mariza; Babron, Marie-Claude; Bartlett, Christopher W; Beyene, Joseph; Bickeböller, Heike; Culverhouse, Robert; Cupples, L Adrienne; Daw, E Warwick; Dupuis, Josée; Falk, Catherine T; Ghosh, Saurabh; Goddard, Katrina A; Goode, Ellen L; Hauser, Elizabeth R; Martin, Lisa J; Martinez, Maria; North, Kari E; Saccone, Nancy L; Schmidt, Silke; Tapper, William; Thomas, Duncan; Tritchler, David; Vieland, Veronica J; Wijsman, Ellen M; Wilcox, Marsha A; Witte, John S; Yang, Qiong; Ziegler, Andreas; Almasy, Laura; MacCluer, Jean W (BioMed Central, 2007-12-18)
  • Cupples, L Adrienne; Beyene, Joseph; Bickeböller, Heike; Daw, E Warwick; Fallin, M Daniele; Gauderman, W James; Ghosh, Saurabh; Goode, Ellen L; Hauser, Elizabeth R; Hinrichs, Anthony; Kent, Jack W; Martin, Lisa J; Martinez, Maria; Neuman, Rosalind J; Province, Michael; Szymczak, Silke; Wilcox, Marsha A; Ziegler, Andreas; MacCluer, Jean W; Almasy, Laura (BioMed Central, 2009-12-15)
  • Seshadri, Sudha; DeStefano, Anita L; Au, Rhoda; Massaro, Joseph M; Beiser, Alexa S; Kelly-Hayes, Margaret; Kase, Carlos S; D'Agostino, Ralph B; DeCarli, Charles; Atwood, Larry D; Wolf, Philip A (BioMed Central, 2007-9-19)
    BACKGROUND: Brain magnetic resonance imaging (MRI) and cognitive tests can identify heritable endophenotypes associated with an increased risk of developing stroke, dementia and Alzheimer's disease (AD). We conducted a ...
  • Lunetta, Kathryn; D'Agostino, Ralph; Karasik, David; Benjamin, Emelia; Guo, Chao-Yu; Govindaraju, Raju; Kiel, Douglas; Kelly-Hayes, Margaret; Massaro, Joseph; Pencina, Michael; et al. (2007)
    BACKGROUND: Family studies and heritability estimates provide evidence for a genetic contribution to variation in the human life span. METHODS:We conducted a genome wide association study (Affymetrix 100K SNP GeneChip) for ...
  • Lunetta, Kathryn L; D'Agostino, Ralph B; Karasik, David; Benjamin, Emelia J; Guo, Chao-Yu; Govindaraju, Raju; Kiel, Douglas P; Kelly-Hayes, Margaret; Massaro, Joseph M; Pencina, Michael J; Seshadri, Sudha; Murabito, Joanne M (BioMed Central, 2007-9-19)
    BACKGROUND: Family studies and heritability estimates provide evidence for a genetic contribution to variation in the human life span. METHODS: We conducted a genome wide association study (Affymetrix 100K SNP GeneChip) ...

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