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Browsing Centers & Institutes by Title

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  • O'Donnell, Christopher J; Cupples, L Adrienne; D'Agostino, Ralph B; Fox, Caroline S; Hoffmann, Udo; Hwang, Shih-Jen; Ingellson, Erik; Liu, Chunyu; Murabito, Joanne M; Polak, Joseph F; Wolf, Philip A; Demissie, Serkalem (BioMed Central, 2007-9-19)
    INTRODUCTION: Subclinical atherosclerosis (SCA) measures in multiple arterial beds are heritable phenotypes that are associated with increased incidence of cardiovascular disease. We conducted a genome-wide association ...
  • Murabito, Joanne M; Rosenberg, Carol L; Finger, Daniel; Kreger, Bernard E; Levy, Daniel; Splansky, Greta Lee; Antman, Karen; Hwang, Shih-Jen (BioMed Central, 2007-9-19)
    BACKGROUND: Breast and prostate cancer are two commonly diagnosed cancers in the United States. Prior work suggests that cancer causing genes and cancer susceptibility genes can be identified. METHODS: We conducted a ...
  • Newton-Cheh, Christopher; Guo, Chao-Yu; Wang, Thomas J; O'Donnell, Christopher J; Levy, Daniel; Larson, Martin G (BioMed Central, 2007-9-19)
    BACKGROUND: Heritable electrocardiographic (ECG) and heart rate variability (HRV) measures, reflecting pacemaking, conduction, repolarization and autonomic function in the heart have been associated with risks for cardiac ...
  • Wilk, Jemma B.; Chen, Ting-hsu; Gottlieb, Daniel J.; Walter, Robert E.; Nagle, Michael W.; Brandler, Brian J.; Myers, Richard H.; Borecki, Ingrid B.; Silverman, Edwin K.; Weiss, Scott T.; O'Connor, George T. (Public Library of Science, 2009-3-20)
    The ratio of forced expiratory volume in one second to forced vital capacity (FEV1/FVC) is a measure used to diagnose airflow obstruction and is highly heritable. We performed a genome-wide association study in 7,691 ...
  • Fox, Caroline S; Heard-Costa, Nancy; Cupples, L Adrienne; Dupuis, Josée; Vasan, Ramachandran S; Atwood, Larry D (BioMed Central, 2007-9-19)
    BACKGROUND: Obesity is related to multiple cardiovascular disease (CVD) risk factors as well as CVD and has a strong familial component. We tested for association between SNPs on the Affymetrix 100K SNP GeneChip and measures ...
  • Kiel, Douglas P; Demissie, Serkalem; Dupuis, Josée; Lunetta, Kathryn L; Murabito, Joanne M; Karasik, David (BioMed Central, 2007-9-19)
    BACKGROUND: Osteoporosis is characterized by low bone mass and compromised bone structure, heritable traits that contribute to fracture risk. There have been no genome-wide association and linkage studies for these traits ...
  • Meigs, James B; Manning, Alisa K; Fox, Caroline S; Florez, Jose C; Liu, Chunyu; Cupples, L Adrienne; Dupuis, Josée (BioMed Central, 2007-9-19)
    BACKGROUND: Susceptibility to type 2 diabetes may be conferred by genetic variants having modest effects on risk. Genome-wide fixed marker arrays offer a novel approach to detect these variants. METHODS: We used the ...
  • Benjamin, Emelia J; Dupuis, Josée; Larson, Martin G; Lunetta, Kathryn L; Booth, Sarah L; Govindaraju, Diddahally R; Kathiresan, Sekar; Keaney, John F; Keyes, Michelle J; Lin, Jing-Ping; Meigs, James B; Robins, Sander J; Rong, Jian; Schnabel, Renate; Vita, Joseph A; Wang, Thomas J; Wilson, Peter WF; Wolf, Philip A; Vasan, Ramachandran S (BioMed Central, 2007-9-19)
    BACKGROUND: Systemic biomarkers provide insights into disease pathogenesis, diagnosis, and risk stratification. Many systemic biomarker concentrations are heritable phenotypes. Genome-wide association studies (GWAS) provide ...
  • Devdariani, Jaba (Boston University Center for the Study of Conflict, Ideology, and Policy, 2002-11)
  • Goltz, Thomas (Boston University Center for the Study of Conflict, Ideology, and Policy, 2001-01)
  • Devdariani, Jaba (Boston University Center for the Study of Conflict, Ideology, and Policy, 2002-09)
  • Lanskoy, Miriam (Boston University Center for the Study of Conflict, Ideology, and Policy, 1997-01)
  • Khutsishvili, Dr. George (Boston University Center for the Study of Conflict, Ideology, and Policy, 1998-03)
  • Bass, Margot S.; Finer, Matt; Jenkins, Clinton N.; Kreft, Holger; Cisneros-Heredia, Diego F.; McCracken, Shawn F.; Pitman, Nigel C. A.; English, Peter H.; Swing, Kelly; Villa, Gorky; Di Fiore, Anthony; Voigt, Christian C.; Kunz, Thomas H. (Public Library of Science, 2010-1-19)
    BACKGROUND. The threats facing Ecuador's Yasuní National Park are emblematic of those confronting the greater western Amazon, one of the world's last high-biodiversity wilderness areas. Notably, the country's second largest ...
  • Szlezák, Nicole A.; Bloom, Barry R.; Jamison, Dean T.; Keusch, Gerald T.; Michaud, Catherine M.; Moon, Suerie; Clark, William C. (Public Library of Science, 2010-1-5)
    In the first in a series of four articles highlighting the changing nature of global health institutions, Nicole Szlezák and colleagues outline the origin and aim of the series.
  • Moon, Suerie; Szlezák, Nicole A.; Michaud, Catherine M.; Jamison, Dean T.; Keusch, Gerald T.; Clark, William C.; Bloom, Barry R. (Public Library of Science, 2010-1-26)
    In the last in a series of four articles highlighting the changing nature of global health institutions, Suerie Moon and colleagues propose future actions to strengthen these institutions.
  • Hahn, Gordon (Boston University Center for the Study of Conflict, Ideology, and Policy, 1990-10)
  • Desai, Tushar J; Cardoso, Wellington V (BioMed Central, 2001-10-9)
    Growth factors mediate tissue interactions and regulate a variety of cellular functions that are critical for normal lung development and homeostasis. Besides their involvement in lung pattern formation, growth and cell ...
  • Hartman, Hyman; Smith, Temple F (BioMed Central, 2010-5-20)
    BACKGROUND. This paper is an attempt to trace the evolution of the ribosome through the evolution of the universal P-loop GTPases that are involved with the ribosome in translation and with the attachment of the ribosome ...
  • Dwyer, Daniel J; Kohanski, Michael A; Hayete, Boris; Collins, James J (2007-03-13)
    Modulation of bacterial chromosomal supercoiling is a function of DNA gyrase-catalyzed strand breakage and rejoining. This reaction is exploited by both antibiotic and proteic gyrase inhibitors, which trap the gyrase ...

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