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Browsing Centers & Institutes by Title

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  • Kimura, Masayuki; Cherkas, Lynn F; Kato, Bernet S; Demissie, Serkalem; Hjelmborg, Jacob B; Brimacombe, Michael; Cupples, Adrienne; Hunkin, Janice L; Gardner, Jefferey P; Lu, Xiaobin; Cao, Xiaojian; Sastrasinh, Malinee; Province, Michael A; Hunt, Steven C; Christensen, Kaare; Levy, Daniel; Spector, Tim D; Aviv, Abraham (Public Library of Science, 2008-2-15)
    Leukocyte telomere length (LTL) is a complex genetic trait. It shortens with age and is associated with a host of aging-related disorders. Recent studies have observed that offspring of older fathers have longer LTLs. We ...
  • Won, Sungho; Wilk, Jemma B.; Mathias, Rasika A.; O'Donnell, Christopher J.; Silverman, Edwin K.; Barnes, Kathleen; O'Connor, George T.; Weiss, Scott T.; Lange, Christoph (Public Library of Science, 2009-11-26)
    For genome-wide association studies in family-based designs, we propose a new, universally applicable approach. The new test statistic exploits all available information about the association, while, by virtue of its design, ...
  • Rosenthal, Rosalind A.; Huffman, Karl D.; Fisette, Leslie W.; Damphousse, Christy A.; Callaway, Wyeth B.; Malfroy, Bernard; Doctrow, Susan R. (Springer-Verlag, 2009-6-6)
    Superoxide dismutase/catalase mimetics, such as salen Mn complexes and certain metalloporphyrins, catalytically neutralize reactive oxygen and nitrogen species, which have been implicated in the pathogenesis of many serious ...
  • Lynch, Tammy (Boston University Center for the Study of Conflict, Ideology, and Policy, 2005-02)
  • Smith, Temple F; Lee, Jung C; Gutell, Robin R; Hartman, Hyman (BioMed Central, 2008-4-22)
    BACKGROUND. The origin and early evolution of the active site of the ribosome can be elucidated through an analysis of the ribosomal proteins' taxonomic block structures and their RNA interactions. Comparison between the ...
  • Walter, J; Ghosh, MK; Kuhn, L; Semrau, K; Sinkala, M; Kankasa, C; Thea, DM; Aldrovandi, GM (BioMed Central, 2009-10-22)
  • Zurovac, Dejan; Ndhlovu, Mickey; Sipilanyambe, Nawa; Chanda, Pascalina; Hamer, Davidson H; Simon, Jon L; Snow, Robert W (BioMed Central, 2007-3-16)
    BACKGROUND Zambia was the first African country to change national antimalarial treatment policy to artemisinin-based combination therapy – artemether-lumefantrine. An evaluation during the early implementation phase ...
  • Kaliyev (Chiharro), Roustam (Boston University Center for the Study of Conflict, Ideology, and Policy, 2001-09)
  • Rosen, Sydney; Fox, Matthew P; Gill, Christopher J (Public Library of Science, 2007-10-16)
    BACKGROUND. Long-term retention of patients in Africa's rapidly expanding antiretroviral therapy (ART) programs for HIV/AIDS is essential for these programs' success but has received relatively little attention. In this ...
  • Pou, Karla M.; Massaro, Joseph M.; Hoffmann, Udo; Lieb, Kathrin; Vasan, Ramachandran S.; O'Donnell, Christopher J.; Fox, Caroline S. (American Diabetes Association, 2011-12-29)
    OBJECTIVE: The prevalence of abdominal obesity exceeds that of general obesity. We sought to determine the prevalence of abdominal subcutaneous and visceral obesity and to characterize the different patterns of fat ...
  • Tobias, Carol R.; Rajabiun, Serena; Franks, Julie; Goldenkranz, Sarah B.; Fine, David N.; Loscher-Hudson, Brenda S.; Colson, Paul W.; Coleman, Sharon M. (Springer US, 2010-3-19)
    People living with HIV (PLWHIV) have been involved in the continuum of HIV care since the early days of the epidemic providing education and prevention services. There is a growing interest in utilizing HIV positive peers ...
  • Meng, Yan A; Yu, Yi; Cupples, L Adrienne; Farrer, Lindsay A; Lunetta, Kathryn L (BioMed Central, 2009-3-5)
    BACKGROUND. Single nucleotide polymorphisms (SNPs) may be correlated due to linkage disequilibrium (LD). Association studies look for both direct and indirect associations with disease loci. In a Random Forest (RF) analysis, ...
  • Sadchikov, Aleksandr (Boston University Center for the Study of Conflict, Ideology, and Policy, 1999-09)
  • Levy, Daniel; DePalma, Steven R; Benjamin, Emelia J; O'Donnell, Christopher J; Parise, Helen; Hirschhorn, Joel N; Vasan, Ramachandran S; Izumo, Seigo; Larson, Martin G (BioMed Central, 2006-5-22)
    BACKGROUND: High-throughput genotyping generates vast amounts of data for analysis; results can be difficult to summarize succinctly. A single project may involve genotyping many genes with multiple variants per gene and ...
  • Zheng, Yu; Anton, Brian P; Roberts, Richard J; Kasif, Simon (BioMed Central, 2005-10-3)
    BACKGROUND. Microbial genomes contain an abundance of genes with conserved proximity forming clusters on the chromosome. However, the conservation can be a result of many factors such as vertical inheritance, or functional ...
  • Lieb, Wolfgang; Sullivan, Lisa M.; Harris, Tamara B.; Roubenoff, Ronenn; Benjamin, Emelia J.; Levy, Daniel; Fox, Caroline S.; Wang, Thomas J.; Wilson, Peter W.; Kannel, William B.; Vasan, Ramachandran S. (American Diabetes Association, 2008-12-29)
    OBJECTIVE: Obesity predisposes individuals to congestive heart failure (CHF) and cardiovascular disease (CVD). Leptin regulates energy homeostasis, is elevated in obesity, and influences ventricular and vascular remodeling. ...
  • Waller, J. Michael (Boston University Center for the Study of Conflict, Ideology, and Policy, 2000-01)
  • Dalgin, Gul S; Alexe, Gabriela; Scanfeld, Daniel; Tamayo, Pablo; Mesirov, Jill P; Ganesan, Shridar; DeLisi, Charles; Bhanot, Gyan (BioMed Central, 2007-8-6)
    BACKGROUND. Clustering analysis of microarray data is often criticized for giving ambiguous results because of sensitivity to data perturbation or clustering techniques used. In this paper, we describe a new method based ...
  • Lynch, Tammy M. (Boston University Center for the Study of Conflict, Ideology, and Policy, 2002-03)
  • Karasik, Theodore (Boston University Center for the Study of Conflict, Ideology, and Policy, 1992-03)

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