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Browsing MED: Medicine Papers by Issue Date

OpenBU

Browsing MED: Medicine Papers by Issue Date

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  • Mydel, Piotr; Takahashi, Yusuke; Yumoto, Hiromichi; Sztukowska, Maryta; Kubica, Malgorzata; Gibson, Frank C; Kurtz, Donald M; Travis, Jim; Collins, L. Vincent; Nguyen, Ky-Anh; Genco, Caroline Attardo; Potempa, Jan (Public Library of Science Pathogens, 2006-7-28)
    The efficient clearance of microbes by neutrophils requires the concerted action of reactive oxygen species and microbicidal components within leukocyte secretory granules. Rubrerythrin (Rbr) is a nonheme iron protein that ...
  • Li, Jian-Liang; Hayden, Michael R; Warby, Simon C; Durr, Alexandra; Morrison, Patrick J; Nance, Martha; Ross, Christopher A; Margolis, Russell L; Rosenblatt, Adam; Squitieri, Ferdinando; Frati, Luigi; Gómez-Tortosa, Estrella; García, Carmen Ayuso; Suchowersky, Oksana; Klimek, Mary Lou; Trent, Ronald JA; McCusker, Elizabeth; Novelletto, Andrea; Frontali, Marina; Paulsen, Jane S; Jones, Randi; Ashizawa, Tetsuo; Lazzarini, Alice; Wheeler, Vanessa C; Prakash, Ranjana; Xu, Gang; Djoussé, Luc; Mysore, Jayalakshmi Srinidhi; Gillis, Tammy; Hakky, Michael; Cupples, L Adrienne; Saint-Hilaire, Marie H; Cha, Jang-Ho J; Hersch, Steven M; Penney, John B; Harrison, Madaline B; Perlman, Susan L; Zanko, Andrea; Abramson, Ruth K; Lechich, Anthony J; Duckett, Ayana; Marder, Karen; Conneally, P Michael; Gusella, James F; MacDonald, Marcy E; Myers, Richard H (BioMed Central, 2006-8-17)
    BACKGROUND: Age at onset of Huntington's disease (HD) is correlated with the size of the abnormal CAG repeat expansion in the HD gene; however, several studies have indicated that other genetic factors also contribute to ...
  • Cole, J Alexander; Rothman, Kenneth J; Cabral, Howard J; Zhang, Yuqing; Farraye, Francis A (BioMed Central, 2006-9-28)
    BACKGROUND. Case descriptions suggest IBS patients are more likely to have other disorders, including migraine, fibromyalgia, and depression. We sought to examine the prevalence of these conditions in cohorts of people ...
  • Zeng, Wenqi; Gillis, Tammy; Hakky, Michael; Djoussé, Luc; Myers, Richard H; MacDonald, Marcy E; Gusella, James F (BioMed Central, 2006-9-7)
    BACKGROUND: In Huntington's disease (HD), age at neurological onset is inversely correlated with the length of the CAG trinucleotide repeat mutation, but can be modified by genetic factors beyond the HD gene. Association ...
  • Lincoln, Alisa K; Liebschutz, Jane M; Chernoff, Miriam; Nguyen, Dana; Amaro, Hortensia (BioMed Central, 2006-9-7)
    BACKGROUND. Despite the importance of identifying co-occurring psychiatric disorders in substance abuse treatment programs, there are few appropriate and validated instruments available to substance abuse treatment staff ...
  • Jain, Nitin B.; Potula, Vijayalakshmi; Schwartz, Joel; Vokonas, Pantel S.; Sparrow, David; Wright, Robert O.; Nie, Huiling; Hu, Howard (National Institute of Environmental Health Sciences, 2007-06)
    BACKGROUND. Lead exposure has been associated with higher blood pressure, hypertension, electrocardiogram abnormalities, and increased mortality from circulatory causes. OBJECTIVE. We assessed the association between bone ...
  • Wang, Florence T.; Hu, Howard; Schwartz, Joel; Weuve, Jennifer; Spiro, Avron S.; Sparrow, David; Nie, Huiling; Silverman, Edwin K.; Weiss, Scott T.; Wright, Robert O. (National Institute of Environmental Health Sciences, 2007-08)
    BACKGROUND. As iron and lead promote oxidative damage, and hemochromatosis (HFE) gene polymorphisms increase body iron burden, HFE variant alleles may modify the lead burden and cognitive decline relationship. OBJECTIVE. ...
  • Peters, Junenette L.; Kubzansky, Laura; McNeely, Eileen; Schwartz, Joel; Spiro, Avron; Sparrow, David; Wright, Robert O.; Nie, Huiling; Hu, Howard (National Institute of Environmental Health Sciences, 2007-08)
    BACKGROUND. Lead exposure and psychological stress have been independently associated with hypertension in various populations, and animal studies suggest that when they co-occur, their effects may be exacerbated. OBJECTIVES. ...
  • Berkenblit, Gail; Sullivan, Lynn; Sosman, James; Gifford, Allen; Cofrancesco, Joseph (Springer-Verlag, 2007-1-12)
  • Alford, Daniel P.; LaBelle, Colleen T.; Richardson, Jessica M.; O'Connell, James J.; Hohl, Carole A.; Cheng, Debbie M.; Samet, Jeffrey H. (Springer-Verlag, 2007-1-17)
    CONTEXT Although office-based opioid treatment with buprenorphine (OBOT-B) has been successfully implemented in primary care settings in the US, its use has not been reported in homeless patients. OBJECTIVE To characterize ...
  • McKinlay, J. B.; Link, C. L.; Freund, K. M.; Marceau, L. D.; O'Donnell, A. B.; Lutfey, K. L. (Springer-Verlag, 2007-1-9)
    BACKGROUND Health services research has documented the magnitude of health care variations. Few studies focus on provider level sources of variation in clinical decision making-for example, which primary care providers are ...
  • Katz, Jeffrey N.; Kessler, Courtenay L.; O'Connell, Andrew; Levine, Sharon A. (Springer-Verlag, 2007-1-9)
    For much of the twentieth century, quality of care was defined specifically in terms of physician characteristics and behaviors. High-quality physicians were well trained, knowledgeable, skillful, and compassionate. More ...
  • Faith, Jeremiah J; Hayete, Boris; Thaden, Joshua T; Mogno, Ilaria; Wierzbowski, Jamey; Cottarel, Guillaume; Kasif, Simon; Collins, James J; Gardner, Timothy S (Public Library of Science, 2007-1-9)
    Machine learning approaches offer the potential to systematically identify transcriptional regulatory interactions from a compendium of microarray expression profiles. However, experimental validation of the performance ...
  • Lam, Jennifer S.; Huang, Haibin; Levitz, Stuart M. (Public Library of Science, 2007-10-10)
    BACKGROUND. An experimental approach for improving vaccine efficacy involves targeting antigens to mannose receptors (MRs) on dendritic cells (DCs) and other professional antigen presenting cells. Previously, we demonstrated ...
  • Hunter, David J; Li, Jiang; LaValley, Michael; Bauer, Doug C; Nevitt, Michael; DeGroot, Jeroen; Poole, Robin; Eyre, David; Guermazi, Ali; Gale, Dan; Felson, David T (BioMed Central, 2007-10-24)
    We used data from a longitudinal observation study to determine whether markers of cartilage turnover could serve as predictors of cartilage loss on magnetic resonance imaging (MRI). We conducted a study of data from the ...
  • Chahine, Teresa; Baccarelli, Andrea; Litonjua, Augusto; Wright, Robert O.; Suh, Helen; Gold, Diane R.; Sparrow, David; Vokonas, Pantel; Schwartz, Joel (National Institute of Environmental Health Sciences, 2007-11)
    BACKGROUND AND OBJECTIVES. We have previously shown that reduced defenses against oxidative stress due to glutathione S-transferase M1 (GSTM1) deletion modify the effects of PM2.5 (fine-particulate air pollution of < 2.5 ...
  • Lafyatis, Robert; Marshak-Rothstein, Ann (BioMed Central, 2007-11-29)
    A series of discoveries over the past several years has provided a new paradigm for understanding autoimmunity in systemic lupus erythematosus. The discoveries of pattern recognition receptors and of how these receptors ...
  • Perlstein, Todd; Weuve, Jennifer; Schwartz, Joel; Sparrow, David; Wright, Robert; Litonjua, Augusto; Nie, Huiling; Hu, Howard (National Institute of Environmental Health Sciences, 2007-12)
    BACKGROUND. Pulse pressure increases with age in industrialized societies as a manifestation of arterial stiffening. Lead accumulates in the vasculature and is associated with vascular oxidative stress, which can promote ...
  • Meng, Yan; Yang, Qiong; Cuenco, Karen T; Cupples, L Adrienne; DeStefano, Anita L; Lunetta, Kathryn L (BioMed Central, 2007-12-18)
    We used the simulated data set from Genetic Analysis Workshop 15 Problem 3 to assess a two-stage approach for identifying single-nucleotide polymorphisms (SNPs) associated with rheumatoid arthritis (RA). In the first stage, ...
  • Lipner, Ettie M.; Law, Melissa A.; Barnett, Elizabeth; Keystone, Jay S.; von Sonnenburg, Frank; Loutan, Louis; Prevots, D. Rebecca; Klion, Amy D.; Nutman, Thomas B. (Public Library of Science, 2007-12-26)
    BACKGROUND. As international travel increases, there is rising exposure to many pathogens not traditionally encountered in the resource-rich countries of the world. Filarial infections, a great problem throughout the ...

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