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Browsing MED: Neurology Papers by Title

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Browsing MED: Neurology Papers by Title

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  • Yip, Agustín G; Green, Robert C; Huyck, Matthew; Cupples, L Adrienne; Farrer, Lindsay A (BioMed Central, 2005-1-12)
    BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAID) use may protect against Alzheimer's disease (AD) risk. We sought examine the association between NSAID use and risk of AD, and potential effect modification by APOE-ε4 ...
  • Heard-Costa, Nancy L.; Zillikens, M. Carola; Monda, Keri L.; Johansson, Åsa; Harris, Tamara B.; Fu, Mao; Haritunians, Talin; Feitosa, Mary F.; Aspelund, Thor; Eiriksdottir, Gudny; Garcia, Melissa; Launer, Lenore J.; Smith, Albert V.; Mitchell, Braxton D.; McArdle, Patrick F.; Shuldiner, Alan R.; Bielinski, Suzette J.; Boerwinkle, Eric; Brancati, Fred; Demerath, Ellen W.; Pankow, James S.; Arnold, Alice M.; Chen, Yii-Der Ida; Glazer, Nicole L.; McKnight, Barbara; Psaty, Bruce M.; Rotter, Jerome I.; Amin, Najaf; Campbell, Harry; Gyllensten, Ulf; Pattaro, Cristian; Pramstaller, Peter P.; Rudan, Igor; Struchalin, Maksim; Vitart, Veronique; Gao, Xiaoyi; Kraja, Aldi; Province, Michael A.; Zhang, Qunyuan; Atwood, Larry D.; Dupuis, Josée; Hirschhorn, Joel N.; Jaquish, Cashell E.; O'Donnell, Christopher J.; Vasan, Ramachandran S.; White, Charles C.; Aulchenko, Yurii S.; Estrada, Karol; Hofman, Albert; Rivadeneira, Fernando; Uitterlinden, André G.; Witteman, Jacqueline C. M.; Oostra, Ben A.; Kaplan, Robert C.; Gudnason, Vilmundur; O'Connell, Jeffrey R.; Borecki, Ingrid B.; van Duijn, Cornelia M.; Cupples, L. Adrienne; Fox, Caroline S.; North, Kari E. (Public Library of Science, 2009-6-26)
    Central abdominal fat is a strong risk factor for diabetes and cardiovascular disease. To identify common variants influencing central abdominal fat, we conducted a two-stage genome-wide association analysis for waist ...
  • Won, Sungho; Wilk, Jemma B.; Mathias, Rasika A.; O'Donnell, Christopher J.; Silverman, Edwin K.; Barnes, Kathleen; O'Connor, George T.; Weiss, Scott T.; Lange, Christoph (Public Library of Science, 2009-11-26)
    For genome-wide association studies in family-based designs, we propose a new, universally applicable approach. The new test statistic exploits all available information about the association, while, by virtue of its design, ...
  • Preston, Brian T; Capellini, Isabella; McNamara, Patrick; Barton, Robert A; Nunn, Charles L (BioMed Central, 2009-1-9)
    BACKGROUND. Sleep is a biological enigma. Despite occupying much of an animal's life, and having been scrutinized by numerous experimental studies, there is still no consensus on its function. Similarly, no hypothesis has ...
  • Kumar, Azad; Greggio, Elisa; Beilina, Alexandra; Kaganovich, Alice; Chan, Diane; Taymans, Jean-Marc; Wolozin, Benjamin; Cookson, Mark R. (Public Library of Science, 2010-1-15)
    Mutations in the gene encoding Leucine-rich repeat kinase 2 (LRRK2) are the most common cause of inherited Parkinson's disease (PD). LRRK2 is a multi-domain protein kinase containing a central catalytic core and a number ...
  • Seitz, Aaron R.; Nanez, Jose E.; Holloway, Steve R.; Watanabe, Takeo (Public Library of Science, 2006-12-20)
    Critical flicker fusion thresholds (CFFT) describe when quick amplitude modulations of a light source become undetectable as the frequency of the modulation increases. The threshold at which CFF occurs has been shown to ...
  • Laramie, Jason M; Wilk, Jemma B; Williamson, Sally L; Nagle, Michael W; Latourelle, Jeanne C; Tobin, Jennifer E; Province, Michael A; Borecki, Ingrid B; Myers, Richard H (BioMed Central, 2008-5-22)
    BACKGROUND: The chromosome 7q32 region is linked to metabolic syndrome and obesity related traits in the Family Heart Study. As part of a fine mapping study of the region, we evaluated the relationship of polymorphisms to ...
  • Strangman, Gary E.; O'Neil-Pirozzi, Therese M.; Supelana, Christina; Goldstein, Richard; Katz, Douglas I.; Glenn, Mel B. (Frontiers Research Foundation, 2010-10-14)
    Cognitive deficits following traumatic brain injury (TBI) commonly include difficulties with memory, attention, and executive dysfunction. These deficits are amenable to cognitive rehabilitation, but optimally selecting ...
  • McNamara, Patrick; Durso, Raymon; Brown, Ariel (Dove Medical Press, 2006)
    OBJECTIVE. To study clinical correlates of religiosity in Parkinson's disease (PD). METHODS. Measures of life goals, religiosity, mood, and neuropsychologic function were assessed in 22 persons with mid-stage PD and 20 ...
  • Wilk, Jemma B; Lash, Timothy L (BioMed Central, 2007-4-4)
    An association between exposure to a risk factor and age-at-onset of disease may reflect an effect on the rate of disease occurrence or an acceleration of the disease process. The difference in age-at-onset arising from ...
  • Latourelle, Jeanne C; Dybdahl, Merete; Destefano, Anita L; Myers, Richard H; Lash, Timothy L (BioMed Central, 2010-4-12)
    BACKGROUND: Women have a reduced risk of developing Parkinson's disease (PD) compared with age-matched men. Neuro-protective effects of estrogen potentially explain this difference. Tamoxifen, commonly used in breast cancer ...
  • Feldman, R G; White, R F (National Institute of Environmental Health Sciences, 1996-04)
    This review describes strategies used by a clinical neurologist in the investigation of neurotoxic disease. It emphasizes the need for a high level of suspicion that environmental substances are capable of producing ...
  • Bardenhagen, Fiona J; Oscar-Berman, Marlene; Bowden, Stephen C (Dove Medical Press, 2007)
    Delayed alternation (DA) and object alternation (OA) tasks traditionally have been used to measure defective response inhibition associated with dysfunction of frontal brain systems. However, these tasks are also sensitive ...
  • Atwood, Larry D; Heard-Costa, Nancy L; Fox, Caroline S; Jaquish, Cashell E; Cupples, L Adrienne (BioMed Central, 2006-1-26)
    BACKGROUND: Previously, we reported significant linkage of body mass index (BMI) to chromosomes 6 and 11 across six examinations, covering 28 years, of the Framingham Heart Study. These results were on all individuals ...
  • Liu-Yesucevitz, Liqun; Bilgutay, Aylin; Zhang, Yong-Jie; Vanderwyde, Tara; Citro, Allison; Mehta, Tapan; Zaarur, Nava; McKee, Ann; Bowser, Robert; Sherman, Michael; Petrucelli, Leonard; Wolozin, Benjamin (Public Library of Science, 2010-10-11)
    Tar DNA Binding Protein-43 (TDP-43) is a principle component of inclusions in many cases of frontotemporal lobar degeneration (FTLD-U) and amyotrophic lateral sclerosis (ALS). TDP-43 resides predominantly in the nucleus, ...
  • Braverman, Eric R; Chen, Amanda Lih-Chuan; Chen, Thomas JH; Schoolfield, John D; Notaro, Alison; Braverman, Dasha; Kerner, Mallory; Blum, Seth H; Arcuri, Vanessa; Varshavskiy, Michael; Damle, Uma; Downs, B William; Waite, Roger L; Oscar-Berman, Marlene; Giordano, John; Blum, Kenneth (Dove Medical Press, 2010-10-15)
    The goal of this study was to determine if impairments detected by the test of variables of attention (TOVA) may be used to predict early attention complaints and memory impairments accurately in a clinical setting. We ...
  • Frank, Samuel (Dove Medical Press, 2010-10-05)
    Huntington disease (HD) is a dominantly inherited progressive neurological disease characterized by chorea, an involuntary brief movement that tends to flow between body regions. HD is typically diagnosed based on clinical ...
  • Chen, Ming-Huei; Larson, Martin G; Hsu, Yi-Hsiang; Peloso, Gina M; Guo, Chao-Yu; Fox, Caroline S; Atwood, Larry D; Yang, Qiong (BioMed Central, 2010-5-14)
    BACKGROUND. Genome-wide association (GWA) studies that use population-based association approaches may identify spurious associations in the presence of population admixture. In this paper, we propose a novel three-stage ...
  • Acerbi, Alberto; McNamara, Patrick; Nunn, Charles L (BioMed Central, 2008-5-14)
    BACKGROUND. All animals thus far studied sleep, but little is known about the ecological factors that generate differences in sleep characteristics across species, such as total sleep duration or division of sleep into ...
  • Meng, Yan; Yang, Qiong; Cuenco, Karen T; Cupples, L Adrienne; DeStefano, Anita L; Lunetta, Kathryn L (BioMed Central, 2007-12-18)
    We used the simulated data set from Genetic Analysis Workshop 15 Problem 3 to assess a two-stage approach for identifying single-nucleotide polymorphisms (SNPs) associated with rheumatoid arthritis (RA). In the first stage, ...

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