OpenBU

Browsing Whitaker Cardiovascular Institute by Title

OpenBU

Browsing Whitaker Cardiovascular Institute by Title

Sort by: Order: Results:

  • Genzen, Jonathan R; Yang, Dan; Ravid, Katya; Bordey, Angelique (BioMed Central, 2009-11-18)
    BACKGROUND: Ependymal cells form a protective monolayer between the brain parenchyma and cerebrospinal fluid (CSF). They possess motile cilia important for directing the flow of CSF through the ventricular system. While ...
  • Cupples, L Adrienne; Arruda, Heather T; Benjamin, Emelia J; D'Agostino, Ralph B; Demissie, Serkalem; DeStefano, Anita L; Dupuis, Josée; Falls, Kathleen M; Fox, Caroline S; Gottlieb, Daniel J; Govindaraju, Diddahally R; Guo, Chao-Yu; Heard-Costa, Nancy L; Hwang, Shih-Jen; Kathiresan, Sekar; Kiel, Douglas P; Laramie, Jason M; Larson, Martin G; Levy, Daniel; Liu, Chun-Yu; Lunetta, Kathryn L; Mailman, Matthew D; Manning, Alisa K; Meigs, James B; Murabito, Joanne M; Newton-Cheh, Christopher; O'Connor, George T; O'Donnell, Christopher J; Pandey, Mona; Seshadri, Sudha; Vasan, Ramachandran S; Wang, Zhen Y; Wilk, Jemma B; Wolf, Philip A; Yang, Qiong; Atwood, Larry D (BioMed Central, 2007-9-19)
    BACKGROUND: The Framingham Heart Study (FHS), founded in 1948 to examine the epidemiology of cardiovascular disease, is among the most comprehensively characterized multi-generational studies in the world. Many collected ...
  • Vasan, Ramachandran S; Larson, Martin G; Aragam, Jayashri; Wang, Thomas J; Mitchell, Gary F; Kathiresan, Sekar; Newton-Cheh, Christopher; Vita, Joseph A; Keyes, Michelle J; O'Donnell, Christopher J; Levy, Daniel; Benjamin, Emelia J (BioMed Central, 2007-9-19)
    BACKGROUND: Echocardiographic left ventricular (LV) measurements, exercise responses to standardized treadmill test (ETT) and brachial artery (BA) vascular function are heritable traits that are associated with cardiovascular ...
  • Deo, Rahul C.; Hunter, Luke; Lewis, Gregory D.; Pare, Guillaume; Vasan, Ramachandran S.; Chasman, Daniel; Wang, Thomas J.; Gerszten, Robert E.; Roth, Frederick P. (Public Library of Science, 2010-2-26)
    Human disease is heterogeneous, with similar disease phenotypes resulting from distinct combinations of genetic and environmental factors. Small-molecule profiling can address disease heterogeneity by evaluating the ...
  • Shaham, Oded; Wei, Ru; Wang, Thomas J; Ricciardi, Catherine; Lewis, Gregory D; Vasan, Ramachandran S; Carr, Steven A; Thadhani, Ravi; Gerszten, Robert E; Mootha, Vamsi K (Nature Publishing GroupMolecular Systems Biology, 2008-08-05)
    Glucose ingestion after an overnight fast triggers an insulin-dependent, homeostatic program that is altered in diabetes. The full spectrum of biochemical changes associated with this transition is currently unknown. We ...
  • Peter, Angela K.; Ko, Christopher Y.; Kim, Michelle H.; Hsu, Nigel; Ouchi, Noriyuki; Rhie, Suhn; Izumiya, Yasuhiro; Zeng, Ling; Walsh, Kenneth; Crosbie, Rachelle H. (Oxford University Press, 2008-11-04)
    Duchenne muscular dystrophy is caused by dystrophin mutations that lead to structural instability of the sarcolemma membrane, myofiber degeneration/regeneration and progressive muscle wasting. Here we show that myogenic ...
  • Lieb, Wolfgang; Sullivan, Lisa M.; Harris, Tamara B.; Roubenoff, Ronenn; Benjamin, Emelia J.; Levy, Daniel; Fox, Caroline S.; Wang, Thomas J.; Wilson, Peter W.; Kannel, William B.; Vasan, Ramachandran S. (American Diabetes Association, 2008-12-29)
    OBJECTIVE: Obesity predisposes individuals to congestive heart failure (CHF) and cardiovascular disease (CVD). Leptin regulates energy homeostasis, is elevated in obesity, and influences ventricular and vascular remodeling. ...
  • Jourd'heuil, Frances L.; Lowery, Anthony M.; Melton, Elaina M.; Mnaimneh, Sanie; Bryan, Nathan S.; Fernandez, Bernadette O.; Park, Joo-Ho; Ha, Chung-Eun; Bhagavan, Nadhipuram V.; Feelisch, Martin; Jourd'heuil, David (Public Library of Science, 2010-12-21)
    BACKGROUND. S-nitrosation - the formation of S-nitrosothiols (RSNOs) at cysteine residues in proteins - is a posttranslational modification involved in signal transduction and nitric oxide (NO) transport. Recent studies ...
  • Grenz, Almut; Osswald, Hartmut; Eckle, Tobias; Yang, Dan; Zhang, Hua; Tran, Zung Vu; Klingel, Karin; Ravid, Katya; Eltzschig, Holger K (Public Library of Science, 2008-6-24)
    BACKGROUND. Acute renal failure from ischemia significantly contributes to morbidity and mortality in clinical settings, and strategies to improve renal resistance to ischemia are urgently needed. Here, we identified a ...
  • Sanoudou, D; Duka, A; Drosatos, K; Hayes, K C; Zannis, V I (Nature Publishing Group, 2009-12-01)
    We have used a new ApoA-I transgenic mouse model to identify by global gene expression profiling, candidate genes that affect lipid and lipoprotein metabolism in response to fenofibrate treatment. Multilevel bioinformatical ...
  • O'Shea, Karen M; Chess, David J; Khairallah, Ramzi J; Hecker, Peter A; Lei, Biao; Walsh, Kenneth; Des Rosiers, Christine; Stanley, William C (BioMed Central, 2010-9-6)
    BACKGROUND Pathological left ventricular (LV) hypertrophy frequently progresses to dilated heart failure with suppressed mitochondrial oxidative capacity. Dietary marine ω-3 polyunsaturated fatty acids (ω-3 PUFA) up-regulate ...

Search OpenBU


Browse

Deposit Materials

Statistics