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Burden of Malaria in Pregnancy in Jharkhand State, India

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dc.contributor.author Hamer, Davidson H en_US
dc.contributor.author Singh, Mrigendra P en_US
dc.contributor.author Wylie, Blair J en_US
dc.contributor.author Yeboah-Antwi, Kojo en_US
dc.contributor.author Tuchman, Jordan en_US
dc.contributor.author Desai, Meghna en_US
dc.contributor.author Udhayakumar, Venkatachalam en_US
dc.contributor.author Gupta, Priti en_US
dc.contributor.author Brooks, Mohamad I en_US
dc.contributor.author Shukla, Manmohan M en_US
dc.contributor.author Awasthy, Kiran en_US
dc.contributor.author Sabin, Lora en_US
dc.contributor.author MacLeod, William B en_US
dc.contributor.author Dash, Aditya P en_US
dc.contributor.author Singh, Neeru en_US
dc.date.accessioned 2012-01-09T20:58:40Z
dc.date.available 2012-01-09T20:58:40Z
dc.date.copyright 2009 en_US
dc.date.issued 2009-9-3 en_US
dc.identifier.citation Hamer, Davidson H, Mrigendra P Singh, Blair J Wylie, Kojo Yeboah-Antwi, Jordan Tuchman, Meghna Desai, Venkatachalam Udhayakumar, Priti Gupta, Mohamad I Brooks, Manmohan M Shukla, Kiran Awasthy, Lora Sabin, William B MacLeod, Aditya P Dash, Neeru Singh. "Burden of malaria in pregnancy in Jharkhand State, India" Malaria Journal 8:210. (2009) en_US
dc.identifier.issn 1475-2875 en_US
dc.identifier.uri http://hdl.handle.net/2144/2948
dc.description.abstract BACKGROUND. Past studies in India included only symptomatic pregnant women and thus may have overestimated the proportion of women with malaria. Given the large population at risk, a cross sectional study was conducted in order to better define the burden of malaria in pregnancy in Jharkhand, a malaria-endemic state in central-east India. METHODS Cross-sectional surveys at antenatal clinics and delivery units were performed over a 12-month period at two district hospitals in urban and semi-urban areas, and a rural mission hospital. Malaria was diagnosed by Giemsa-stained blood smear and/or rapid diagnostic test using peripheral or placental blood. RESULTS 2,386 pregnant women were enrolled at the antenatal clinics and 718 at the delivery units. 1.8% (43/2382) of the antenatal clinic cohort had a positive diagnostic test for malaria (53.5% Plasmodium falciparum, 37.2% Plasmodium vivax, and 9.3% mixed infections). Peripheral parasitaemia was more common in pregnant women attending antenatal clinics in rural sites (adjusted relative risk [aRR] 4.31, 95%CI 1.84-10.11) and in those who were younger than 20 years (aRR 2.68, 95%CI 1.03-6.98). Among delivery unit participants, 1.7% (12/717) had peripheral parasitaemia and 2.4% (17/712) had placental parasitaemia. Women attending delivery units were more likely to be parasitaemic if they were in their first or second pregnancy (aRR 3.17, 95%CI 1.32-7.61), had fever in the last week (aRR 5.34, 95%CI 2.89-9.90), or had rural residence (aRR 3.10, 95%CI 1.66-5.79). Malaria control measures including indoor residual spraying (IRS) and untreated bed nets were common, whereas insecticide-treated bed nets (ITN) and malaria chemoprophylaxis were rarely used. CONCLUSION The prevalence of malaria among pregnant women was relatively low. However, given the large at-risk population in this malaria-endemic region of India, there is a need to enhance ITN availability and use for prevention of malaria in pregnancy, and to improve case management of symptomatic pregnant women. en_US
dc.description.sponsorship The United States Agency for International Development (9GHS-A-00-03-00020-00); Child and Family Applied Research project at Boston University en_US
dc.language.iso en en_US
dc.publisher BioMed Central en_US
dc.rights Copyright 2009 Hamer et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. en_US
dc.rights.uri http://creativecommons.org/licenses/by/2.0 en_US
dc.title Burden of Malaria in Pregnancy in Jharkhand State, India en_US
dc.type article en_US
dc.identifier.doi 10.1186/1475-2875-8-210 en_US
dc.identifier.pubmedid 19728882 en_US
dc.identifier.pmcid 2744702 en_US


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Copyright 2009 Hamer et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Except where otherwise noted, this item's license is described as Copyright 2009 Hamer et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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