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Browsing Department of Medicine by Subject "Lead"

OpenBU

Browsing Department of Medicine by Subject "Lead"

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  • Wright, Robert O.; Schwartz, Joel; Wright, Rosalind J.; Bollati, Valentina; Tarantini, Letizia; Park, Sung Kyun; Hu, Howard; Sparrow, David; Vokonas, Pantel; Baccarelli, Andrea (National Institute of Environmental Health Sciences, 2010-06)
    BACKGROUND. DNA methylation is an epigenetic mark that regulates gene expression. Changes in DNA methylation within white blood cells may result from cumulative exposure to environmental metals such as lead. Bone lead, a ...
  • Park, Sung Kyun; Hu, Howard; Wright, Robert O.; Schwartz, Joel; Cheng, Yawen; Sparrow, David; Vokonas, Pantel S.; Weisskopf, Marc G. (National Institute of Environmental Health Sciences, 2009-01)
    BACKGROUND. Cumulative exposure to lead has been shown to be associated with depression of electrocardiographic conduction, such as QT interval (time from start of the Q wave to end of the T wave). Because iron can enhance ...
  • Wang, Florence T.; Hu, Howard; Schwartz, Joel; Weuve, Jennifer; Spiro, Avron S.; Sparrow, David; Nie, Huiling; Silverman, Edwin K.; Weiss, Scott T.; Wright, Robert O. (National Institute of Environmental Health Sciences, 2007-08)
    BACKGROUND. As iron and lead promote oxidative damage, and hemochromatosis (HFE) gene polymorphisms increase body iron burden, HFE variant alleles may modify the lead burden and cognitive decline relationship. OBJECTIVE. ...

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