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Browsing College of Engineering by Title

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  • Riehl, William J.; Krapivsky, Paul L.; Redner, Sidney; Segrè, Daniel (Public Library of Science, 2010-4-1)
    Metabolic networks perform some of the most fundamental functions in living cells, including energy transduction and building block biosynthesis. While these are the best characterized networks in living systems, understanding ...
  • Ding, Chunming; Maier, Esther; Roscher, Adelbert A; Braun, Andreas; Cantor, Charles R (BioMed Central, 2004-5-5)
    BACKGROUND. For a diploid organism such as human, the two alleles of a particular gene can be expressed at different levels due to X chromosome inactivation, gene imprinting, different local promoter activity, or mRNA ...
  • Hayete, Boris; Gardner, Timothy S; Collins, James J (2007-02-13)
  • Burroughs, A Maxwell; Balaji, S; Iyer, Lakshminarayan M; Aravind, L (BioMed Central, 2007-7-2)
    BACKGROUND. The β-grasp fold (β-GF), prototyped by ubiquitin (UB), has been recruited for a strikingly diverse range of biochemical functions. These functions include providing a scaffold for different enzymatic active ...
  • Sridhar, Sriram; Schembri, Frank; Zeskind, Julie; Shah, Vishal; Gustafson, Adam M; Steiling, Katrina; Liu, Gang; Dumas, Yves-Martine; Zhang, Xiaohui; Brody, Jerome S; Lenburg, Marc E; Spira, Avrum (BioMed Central, 2008-5-30)
    BACKGROUND: Cigarette smoking is a leading cause of preventable death and a significant cause of lung cancer and chronic obstructive pulmonary disease. Prior studies have demonstrated that smoking creates a field of molecular ...
  • Yanai, Itai; DeLisi, Charles (BioMed Central, 2002-10-25)
    Comparative genomics provides at least three methods for identifying functional links between genes: examination of phylogenetic distributions, analysis of conserved proximity and observations of fusions of genes into a ...
  • Wilson, Preston Scot (Boston University, 2002)
    In the ocean, natural and artificial processes generate clouds of bubbles which scatter and attenuate sound. Measurements have shown that at the individual bubble resonance frequency, sound propagation in this medium is ...
  • Voevodski, Konstantin; Teng, Shang-Hua; Xia, Yu (BioMed Central, 2009-11-29)
    BACKGROUND. Protein-protein interaction (PPI) networks enable us to better understand the functional organization of the proteome. We can learn a lot about a particular protein by querying its neighborhood in a PPI network ...
  • Alekseev, Kirill N; Cannon, Ethan H; McKinney, Jonathan C; Kusmartsev, Feodor V; Campbell, David K (1997-09-02)
    We study a resistively shunted semiconductor superlattice subject to a high-frequency electric field. Using a balance equation approach that incorporates the influence of the electric circuit, we determine ...
  • Sullivan, James C.; Ryan, Joseph F.; Watson, James A.; Webb, Jeramy; Mullikin, James C.; Rokhsar, Daniel; Finnerty, John R. (Oxford University Press, 2005-12-28)
    StellaBase, the Nematostella vectensis Genomics Database, is a web-based resource that will facilitate desktop and bench-top studies of the starlet sea anemone. Nematostella is an emerging model organism that has already ...
  • Chitnis, Parag Vijay. (2007-11-04)
    Shock wave lithotripsy is the preferred treatment modality for kidney stones in the United States. Despite clinical use for over twenty-five years, the mechanisms of stone fragmentation are still under debate. A piezoelectric ...
  • Oşan, Remus; Zhu, Liping; Shoham, Shy; Tsien, Joe Z. (Public Library of Science, 2007-5-2)
    Recent advances in large-scale ensemble recordings allow monitoring of activity patterns of several hundreds of neurons in freely behaving animals. The emergence of such high-dimensional datasets poses challenges for the ...
  • Plasterer, Thomas N; Smith, Temple F; Mohr, Scott C (BioMed Central, 2001-06-01)
    BACKGROUND. We have constructed Bayesian prior-based, amino-acid sequence profiles for the complete yeast mitochondrial proteome and used them to develop methods for identifying and characterizing the context of protein ...
  • Alekseev, Kirill N; Cannon, Ethan H; McKinney, Jonathan C; Kusmartsev, Feodor V; Campbell, David K (2001-04-09)
    We study the motion of electrons in a single miniband of a semiconductor superlattice driven by THz electric field polarized along the growth direction. We work in the semiclassical balance-equation model, ...
  • Liu, Donglin; Brockman, J. Michael; Dass, Brinda; Hutchins, Lucie N.; Singh, Priyam; McCarrey, John R.; MacDonald, Clinton C.; Graber, Joel H. (Oxford University Press, 2006-12-08)
    Gene expression and processing during mouse male germ cell maturation (spermatogenesis) is highly specialized. Previous reports have suggested that there is a high incidence of alternative 3′-processing in male germ cell ...
  • Li, Zheng; Chan, Christina (BioMed Central, 2009-3-10)
    Drug-induced liver toxicity is one of the leading causes of acute liver failure in the United States, exceeding all other causes combined. The objective of this paper is to describe systems biology methods for identifying ...
  • Reddy, T. B. K.; Riley, Robert; Wymore, Farrell; Montgomery, Phillip; DeCaprio, Dave; Engels, Reinhard; Gellesch, Marcel; Hubble, Jeremy; Jen, Dennis; Jin, Heng; Koehrsen, Michael; Larson, Lisa; Mao, Maria; Nitzberg, Michael; Sisk, Peter; Stolte, Christian; Weiner, Brian; White, Jared; Zachariah, Zachariah K.; Sherlock, Gavin; Galagan, James E.; Ball, Catherine A.; Schoolnik, Gary K. (Nucleic Acids Research, 2009-1)
    The effective control of tuberculosis (TB) has been thwarted by the need for prolonged, complex and potentially toxic drug regimens, by reliance on an inefficient vaccine and by the absence of biomarkers of clinical status. ...
  • Guo, Yuchun; Eichler, Gabriel S.; Feng, Ying; Ingber, Donald E.; Huang, Sui (Hindawi Publishing Corporation, 2006-11-2)
    Genome-wide gene expression profile studies encompass increasingly large number of samples, posing a challenge to their presentation and interpretation without losing the notion that each transcriptome constitutes a complex ...
  • Gustafson, Adam M; Snitkin, Evan S; Parker, Stephen CJ; DeLisi, Charles; Kasif, Simon (BioMed Central, 2006-10-19)
    BACKGROUND: The identification of genes essential for survival is of theoretical importance in the understanding of the minimal requirements for cellular life, and of practical importance in the identification of potential ...
  • Bais, Manish; McLean, Jody; Sebastiani, Paola; Young, Megan; Wigner, Nathan; Smith, Temple; Kotton, Darrell N.; Einhorn, Thomas A.; Gerstenfeld, Louis C. (Public Library of Science, 2009-5-5)
    Fractures are among the most common human traumas. Fracture healing represents a unique temporarily definable post-natal process in which to study the complex interactions of multiple molecular events that regulate ...

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