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Browsing ENG: Biomedical Engineering: Scholarly Papers by Title

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Browsing ENG: Biomedical Engineering: Scholarly Papers by Title

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  • Alexe, G.; Dalgin, G.S.; Ramaswamy, R.; DeLisi, C.; Bhanot, G. (Libertas Academica, 2007-2-19)
    Molecular stratification of disease based on expression levels of sets of genes can help guide therapeutic decisions if such classifications can be shown to be stable against variations in sample source and data perturbation. ...
  • Rosen, Jennifer; Suh, Hyunsuk; Lee, Stephanie; Aamar, Ousama; Bigio, Irving (BioMed Central, 2010-10-29)
  • Jain, Abhishek; Munn, Lance L. (Public Library of Science, 2009-9-21)
    Microfabrication of polydimethylsiloxane (PDMS) devices has provided a new set of tools for studying fluid dynamics of blood at the scale of real microvessels. However, we are only starting to understand the power and ...
  • Parikh, Jignesh R.; Klinger, Bertram; Xia, Yu; Marto, Jarrod A.; Blüthgen, Nils (Oxford University Press, 2010-5-21)
    High-throughput gene-expression studies result in lists of differentially expressed genes. Most current meta-analyses of these gene lists include searching for significant membership of the translated proteins in various ...
  • Khurana, Jaspreet S.; Xu, Jia; Weng, Zhiping; Theurkauf, William E. (Public Library of Science, 2010-12-16)
    Transposons and other selfish DNA elements can be found in all phyla, and mobilization of these elements can compromise genome integrity. The piRNA (PIWI-interacting RNA) pathway silences transposons in the germline, but ...
  • Esue, Osigwe; Rupprecht, Laura; Sun, Sean X.; Wirtz, Denis (Public Library of Science, 2010-1-25)
    BACKGROUND. Crescentin, the recently discovered bacterial intermediate filament protein, organizes into an extended filamentous structure that spans the length of the bacterium Caulobacter crescentus and plays a critical ...
  • Klitgord, Niels; Segrè, Daniel (Public Library of Science, 2010-11-18)
    Interactions between microbial species are sometimes mediated by the exchange of small molecules, secreted by one species and metabolized by another. Both one-way (commensal) and two-way (mutualistic) interactions may ...
  • Yanai, Itai; Wolf, Yuri I; Koonin, Eugene V (BioMed Central, 2002-04-26)
    BACKGROUND. Gene fusions can be used as tools for functional prediction and also as evolutionary markers. Fused genes often show a scattered phyletic distribution, which suggests a role for processes other than vertical ...
  • Bangera, Nitin B.; Schomer, Donald L.; Dehghani, Nima; Ulbert, Istvan; Cash, Sydney; Papavasiliou, Steve; Eisenberg, Solomon R.; Dale, Anders M.; Halgren, Eric (Springer US, 2010-1-9)
    Forward solutions with different levels of complexity are employed for localization of current generators, which are responsible for the electric and magnetic fields measured from the human brain. The influence of brain ...
  • Wei, Feng; Wang, Guo-Du; Zhang, Chao; Shokat, Kevan M; Wang, Huimin; Tsien, Joe Z; Liauw, Jason; Zhuo, Min (BioMed Central, 2006-6-15)
    Activity-dependent synaptic plasticity is known to be important in learning and memory, persistent pain and drug addiction. Glutamate NMDA receptor activation stimulates several protein kinases, which then trigger biochemical ...
  • Anton, Brian P.; Russell, Susan P.; Vertrees, Jason; Kasif, Simon; Raleigh, Elisabeth A.; Limbach, Patrick A.; Roberts, Richard J. (2010-5-14)
    Methylthiotransferases (MTTases) are a closely related family of proteins that perform both radical-S-adenosylmethionine (SAM) mediated sulfur insertion and SAM-dependent methylation to modify nucleic acid or protein targets ...
  • Wu, Chang-Jiun; Kasif, Simon (Oxford University Press, 2005-06-27)
    The advent of microarray technology has revolutionized the search for genes that are differentially expressed across a range of cell types or experimental conditions. Traditional clustering methods, such as hierarchical ...
  • Wu, Jie; Hu, Zhenjun; DeLisi, Charles (BioMed Central, 2006-2-17)
    BACKGROUND. Phylogenetic analysis is emerging as one of the most informative computational methods for the annotation of genes and identification of evolutionary modules of functionally related genes. The effectiveness ...
  • Lee, Soohyun; Kohane, Isaac; Kasif, Simon (2005)
    BACKGROUND:Recent advances in genome sequencing suggest a remarkable conservation in gene content of mammalian organisms. The similarity in gene repertoire present in different organisms has increased ...
  • Lee, Soohyun; Kohane, Isaac; Kasif, Simon (BioMed Central, 2005-11-27)
    BACKGROUND: Recent advances in genome sequencing suggest a remarkable conservation in gene content of mammalian organisms. The similarity in gene repertoire present in different organisms has increased interest in studying ...
  • Ku, Manching; Koche, Richard P.; Rheinbay, Esther; Mendenhall, Eric M.; Endoh, Mitsuhiro; Mikkelsen, Tarjei S.; Presser, Aviva; Nusbaum, Chad; Xie, Xiaohui; Chi, Andrew S.; Adli, Mazhar; Kasif, Simon; Ptaszek, Leon M.; Cowan, Chad A.; Lander, Eric S.; Koseki, Haruhiko; Bernstein, Bradley E. (Public Library of Science, 2008-10-31)
    In embryonic stem (ES) cells, bivalent chromatin domains with overlapping repressive (H3 lysine 27 tri-methylation) and activating (H3 lysine 4 tri-methylation) histone modifications mark the promoters of more than 2,000 ...
  • Dwyer, Daniel J; Kohanski, Michael A; Hayete, Boris; Collins, James J (2007)
    Modulation of bacterial chromosomal supercoiling is a function of DNA gyrase-catalyzed strand breakage and rejoining. This reaction is exploited by both antibiotic and proteic gyrase inhibitors, which trap ...
  • Dwyer, Daniel J; Kohanski, Michael A; Hayete, Boris; Collins, James J (2007-03-13)
    Modulation of bacterial chromosomal supercoiling is a function of DNA gyrase-catalyzed strand breakage and rejoining. This reaction is exploited by both antibiotic and proteic gyrase inhibitors, which trap the gyrase ...
  • Upile, Tahwinder; Jerjes, Waseem; Sterenborg, Henricus JCM; El-Naggar, Adel K; Sandison, Ann; Witjes, Max JH; Biel, Merrill A; Bigio, Irving; Wong, Brian JF; Gillenwater, Ann; MacRobert, Alexander J; Robinson, Dominic J; Betz, Christian S; Stepp, Herbert; Bolotine, Lina; McKenzie, Gordon; Mosse, Charles Alexander; Barr, Hugh; Chen, Zhongping; Berg, Kristian; D'Cruz, Anil K; Stone, Nicholas; Kendall, Catherine; Fisher, Sheila; Leunig, Andreas; Olivo, Malini; Richards-Kortum, Rebecca; Soo, Khee Chee; Bagnato, Vanderlei; Choo-Smith, Lin-Ping; Svanberg, Katarina; Tan, I Bing; Wilson, Brian C; Wolfsen, Herbert; Yodh, Arjun G; Hopper, Colin (BioMed Central, 2009-07-13)
    Review paper and Proceedings of the Inaugural Meeting of the Head and Neck Optical Diagnostics Society (HNODS) on March 14th 2009 at University College London. The aim of our research must be to provide breakthrough ...
  • Lehár, Joseph; Krueger, Andrew; Zimmermann, Grant; Borisy, Alexis (Nature Publishing Group, 2008-08-05)
    Biological systems are robust, in that they can maintain stable phenotypes under varying conditions or attacks. Biological systems are also complex, being organized into many functional modules that communicate through ...

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