OpenBU

Browsing Chemistry by Title

OpenBU

Browsing Chemistry by Title

Sort by: Order: Results:

  • Cencic, Regina; Carrier, Marilyn; Galicia-Vázquez, Gabriela; Bordeleau, Marie-Eve; Sukarieh, Rami; Bourdeau, Annie; Brem, Brigitte; Teodoro, Jose G.; Greger, Harald; Tremblay, Michel L.; Porco, John A.; Pelletier, Jerry (Public Library of Science, 2009-4-29)
    BACKGROUND. Flavaglines are a family of natural products from the genus Aglaia that exhibit anti-cancer activity in vitro and in vivo and inhibit translation initiation. They have been shown to modulate the activity of ...
  • Mulcahy, Seann P. (2012-01-03)
    A convenient multi-week experiment that results in the formation of two new stereocenters starting from enantiopure norephedrine as the chiral auxiliary. This experiment uses a variety of purification techniques, including ...
  • Mulcahy, Seann P. (2011-10-11)
    A simple experiment to demonstrate nucleophilic addition to a carbonyl. Sodium borohydride-mediated reduction of fluorenone is a fast and high-yielding reaction that is suitable for beginning students. Students isolate ...
  • Kahn, Michael I.; Golen, James A.; Rheingold, Arnold L.; Doerrer, Linda H. (International Union of Crystallography, 2009-8-26)
    The crystal structure of the title compound, [PtBr(C15H11N3)][AuBr2]·(CH3)2SO, exhibits infinite chains of {PtAuPt}∞ metallophilic interactions along the b axis. Two cations and one anion stack in a trimer with a unique ...
  • Ralifo, Paul (2012-04-16)
    NMR Spectral data of Carvone
  • Mulcahy, Seann P. (2012-01-03)
    A short aldol condensation reaction that produces differentially-substituted dibenzylideneketones whose UV-Vis spectra can be determined. This experiment allows students to construct structure-activity relationships in the ...
  • Parikh, Jignesh R.; Klinger, Bertram; Xia, Yu; Marto, Jarrod A.; Blüthgen, Nils (Oxford University Press, 2010-5-21)
    High-throughput gene-expression studies result in lists of differentially expressed genes. Most current meta-analyses of these gene lists include searching for significant membership of the translated proteins in various ...
  • Mulcahy, Seann P.; Bishop, Joshua (2011-07-14)
    A simple procedure for the isolation of caffeine from energy drinks by solid phase extraction on a C18 cartridge. Quantitative analysis of the amount of caffeine by LC/MS is determined by referencing a standard curve.
  • Voevodski, Konstantin; Teng, Shang-Hua; Xia, Yu (BioMed Central, 2009-9-18)
    BACKGROUND. Protein-protein interactions (PPIs) play fundamental roles in nearly all biological processes, and provide major insights into the inner workings of cells. A vast amount of PPI data for various organisms is ...
  • Mulcahy, Seann P. (2012-01-03)
    A microwave-accelerated synthesis of volatile aromatic esters is described in this convenient Fisher esterification reaction. Students perform a liquid-liquid extraction to isolate crude product which they purify by ...
  • Mulcahy, Seann P. (2011-10-15)
    An introductory laboratory on the identification of analgesics in an unknown sample. Ideal for the first week of an organic chemistry sequence to get students familiar with their surroundings. Students extract, isolate, ...
  • Linghu, Bolan; Snitkin, Evan S; Hu, Zhenjun; Xia, Yu; DeLisi, Charles (BioMed Central, 2009-09-03)
    An evidence-weighted functional-linkage network of human genes reveals associations among diseases that share no known disease genes and have dissimilar phenotypes. We integrate 16 genomic features to construct an ...
  • Mulcahy, Seann P. (2011-10-11)
    A convenient preparation of substituted benzoic acids from Grignard additions to solid carbon dioxide. Students create a library of carboxylic acids by using differentially substituted, commercially available aryl bromides, ...
  • Xia, Yu; Franzosa, Eric A.; Gerstein, Mark B. (Public Library of Science, 2009-6-12)
    Rates of evolution differ widely among proteins, but the causes and consequences of such differences remain under debate. With the advent of high-throughput functional genomics, it is now possible to rigorously assess the ...
  • Mulcahy, Seann P. (2011-07-14)
    A two-week multi-step experiment that introduces students to mechanistic organic chemistry and substituent effects. A simple preparation of differentially substituted para-nitrophenyl benzoates is followed by ester hydrolysis ...
  • Mulcahy, Seann P.; Evans, Thomas; Rossi, Lauren (2011-07-14)
    Excellent laboratory procedure for a small focused library of dihydropyrimidinones. Good example of a multicomponent reaction performed using microwave irradiation.
  • Snyder, John K. (2012-10-26)
    Examples of NMR problems used in various homeworks and exams for sophomore organic chemistry
  • Snyder, John K. (2012-10-26)
    Additional NMR problems for sophomore organic chemistry
  • Wang, Yong; Zhang, Xiang-Sun; Xia, Yu (2009-10)
    Transcriptional cooperativity among several transcription factors (TFs) is believed to be the main mechanism of complexity and precision in transcriptional regulatory programs. Here, we present a Bayesian network framework ...
  • Wang, Yong; Franzosa, Eric A.; Zhang, Xiang-Sun; Xia, Yu (Oxford University Press, 2010-5-13)
    When averaged over the full yeast protein–protein interaction and transcriptional regulatory networks, protein hubs with many interaction partners or regulators tend to evolve significantly more slowly due to increased ...

Search OpenBU


Browse

Deposit Materials

Statistics