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Browsing Chemistry by Title

OpenBU

Browsing Chemistry by Title

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  • Snyder, John
    Two problems related to alkene and alkyne chemistry
  • Cencic, Regina; Carrier, Marilyn; Galicia-Vázquez, Gabriela; Bordeleau, Marie-Eve; Sukarieh, Rami; Bourdeau, Annie; Brem, Brigitte; Teodoro, Jose G.; Greger, Harald; Tremblay, Michel L.; Porco, John A.; Pelletier, Jerry (Public Library of Science, 2009-4-29)
    BACKGROUND. Flavaglines are a family of natural products from the genus Aglaia that exhibit anti-cancer activity in vitro and in vivo and inhibit translation initiation. They have been shown to modulate the activity of ...
  • Mulcahy, Seann P. (2012-01-03)
    A convenient multi-week experiment that results in the formation of two new stereocenters starting from enantiopure norephedrine as the chiral auxiliary. This experiment uses a variety of purification techniques, including ...
  • Snyder, John K. (2014)
  • Snyder, John K. (2014)
  • Mulcahy, Seann P. (2011-10-11)
    A simple experiment to demonstrate nucleophilic addition to a carbonyl. Sodium borohydride-mediated reduction of fluorenone is a fast and high-yielding reaction that is suitable for beginning students. Students isolate ...
  • Kahn, Michael I.; Golen, James A.; Rheingold, Arnold L.; Doerrer, Linda H. (International Union of Crystallography, 2009-8-26)
    The crystal structure of the title compound, [PtBr(C15H11N3)][AuBr2]·(CH3)2SO, exhibits infinite chains of {PtAuPt}∞ metallophilic interactions along the b axis. Two cations and one anion stack in a trimer with a unique ...
  • Ralifo, Paul (2012-04-16)
    NMR Spectral data of Carvone
  • Ingle, Shakti; Azad, Robert N.; Jain, Swapan S.; Tullius, Thomas D. (Oxford University Press, 2014-10-13)
    While hydroxyl radical cleavage is widely used to map RNA tertiary structure, lack of mechanistic understanding of strand break formation limits the degree of structural insight that can be obtained from this experiment. ...
  • Mulcahy, Seann P. (2012-01-03)
    A short aldol condensation reaction that produces differentially-substituted dibenzylideneketones whose UV-Vis spectra can be determined. This experiment allows students to construct structure-activity relationships in the ...
  • Parikh, Jignesh R.; Klinger, Bertram; Xia, Yu; Marto, Jarrod A.; Blüthgen, Nils (Oxford University Press, 2010-5-21)
    High-throughput gene-expression studies result in lists of differentially expressed genes. Most current meta-analyses of these gene lists include searching for significant membership of the translated proteins in various ...
  • Snyder, John K. (2014)
  • Mulcahy, Seann P.; Bishop, Joshua (2011-07-14)
    A simple procedure for the isolation of caffeine from energy drinks by solid phase extraction on a C18 cartridge. Quantitative analysis of the amount of caffeine by LC/MS is determined by referencing a standard curve.
  • Voevodski, Konstantin; Teng, Shang-Hua; Xia, Yu (BioMed Central, 2009-9-18)
    BACKGROUND. Protein-protein interactions (PPIs) play fundamental roles in nearly all biological processes, and provide major insights into the inner workings of cells. A vast amount of PPI data for various organisms is ...
  • Mulcahy, Seann P. (2012-01-03)
    A microwave-accelerated synthesis of volatile aromatic esters is described in this convenient Fisher esterification reaction. Students perform a liquid-liquid extraction to isolate crude product which they purify by ...
  • Mulcahy, Seann P. (2011-10-15)
    An introductory laboratory on the identification of analgesics in an unknown sample. Ideal for the first week of an organic chemistry sequence to get students familiar with their surroundings. Students extract, isolate, ...
  • Strom, Kyle R.; Impastato, Anna C.; Moy, Kenneth J.; Landreth, Adrian J. (REU 2014); Snyder*, John K. (American Chemical Society, 2015-04-17)
    Cyclization of 1,6-diynes promoted by stoichiometric Ga(III) halides produces vinyl halides in good to excellent yields. Under acidic conditions, initially formed iodocyclization products undergo in situ Friedel-Crafts ...
  • Chiu, Tsu-Pei; Yang, Lin; Zhou, Tianyin; Main, Bradley; Parker, Stephen C.J.; Nuzhdin, Sergey V.; Tullius, Thomas D.; Rohs, Remo (Oxford University Press, 2014-10-17)
    Many regulatory mechanisms require a high degree of specificity in protein-DNA binding. Nucleotide sequence does not provide an answer to the question of why a protein binds only to a small subset of the many putative ...
  • Linghu, Bolan; Snitkin, Evan S; Hu, Zhenjun; Xia, Yu; DeLisi, Charles (BioMed Central, 2009-09-03)
    An evidence-weighted functional-linkage network of human genes reveals associations among diseases that share no known disease genes and have dissimilar phenotypes. We integrate 16 genomic features to construct an ...

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