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Browsing by Author "Ahern, Thomas P"

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Concordance of Metabolic Enzyme Genotypes Assayed from Paraffin-Embedded, Formalin-Fixed Breast Tumors and Normal Lymphatic Tissue

Ahern, Thomas P; Christensen, Mariann; Cronin-Fenton, Deirdre P; Lunetta, Kathryn L; Rosenberg, Carol L; Sørensen, Henrik Toft; Lash, Timothy L; Hamilton-Dutoit, Stephen (Dove Medical Press, 2010-10-22)

OBJECTIVES: Translational epidemiology studies often use archived tumor specimens to evaluate genetic hypotheses involving cancer outcomes. When the exposure of interest is a germline polymorphism, a key concern is whether ...
Digoxin Treatment Is Associated with an Increased Incidence of Breast Cancer: A Population-Based Case-Control Study

Ahern, Thomas P; Lash, Timothy L; Sørensen, Henrik T; Pedersen, Lars (BioMed Central, 2008-12-3)

INTRODUCTION. Laboratory and epidemiologic studies have suggested a modifying effect of cardiac glycosides (for example, digoxin and digitoxin) on cancer risk. We explored the association between digoxin treatment and ...
Potential Misinterpretations Caused by Collapsing Upper Categories of Comorbidity Indices: An Illustration from a Cohort of Older Breast Cancer Survivors

Ahern, Thomas P; Bosco, Jaclyn LF; Silliman, Rebecca A; Yood, Marianne Ulcickas; Field, Terry S; Wei, Feifei; Lash, Timothy L (Dove Medical Press, 2009-8-9)

BACKGROUND: Comorbidity indices summarize complex medical histories into concise ordinal scales, facilitating stratification and regression in epidemiologic analyses. Low subject prevalence in the highest strata of a ...

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