Browsing by Author "Levy, Daniel"

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Browsing by Author "Levy, Daniel"

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  • Lieb, Wolfgang; Pencina, Michael J.; Lanier, Katherine J.; Tofler, Geoffrey H.; Levy, Daniel; Fox, Caroline S.; Wang, Thomas J.; D'Agostino, Ralph B.; Vasan, Ramachandran S. (American Diabetes Association, 2011-12-29)
    OBJECTIVE: Parental obesity is a risk factor for offspring obesity. It is unclear whether parental obesity also confers risk for obesity-associated conditions (e.g., a proinflammatory or prothrombotic state) in the absence ...
  • Molenaar, Esther A.; Hwang, Shih-Jen; Vasan, Ramachandran S.; Grobbee, Diederick E.; Meigs, James B.; D'Agostino, Ralph B.; Levy, Daniel; Fox, Caroline S. (American Diabetes Association, 2011-12-29)
    OBJECTIVE: Obesity is associated with an increased risk for cardiovascular disease (CVD). We sought to determine rates of treatment and control of CVD risk factors among normal weight, overweight, and obese individuals in ...
  • Atwood, Larry D; Heard-Costa, Nancy L; Cupples, L Adrienne; Levy, Daniel (BioMed Central, 2003-12-31)
    BACKGROUND. The repeated measures in the Framingham Heart Study in the Genetic Analysis Workshop 13 data set allow us to test for consistency of linkage results within a study across time. We compared regression-based ...
  • Cupples, L Adrienne; Yang, Qiong; Demissie, Serkalem; Copenhafer, Donna; Levy, Daniel (BioMed Central, 2003-12-31)
  • Levy, Daniel; Larson, Martin G; Benjamin, Emelia J; Newton-Cheh, Christopher; Wang, Thomas J; Hwang, Shih-Jen; Vasan, Ramachandran S; Mitchell, Gary F (BioMed Central, 2007-9-19)
    BACKGROUND: About one quarter of adults are hypertensive and high blood pressure carries increased risk for heart disease, stroke, kidney disease and death. Increased arterial stiffness is a key factor in the pathogenesis ...
  • Larson, Martin G; Atwood, Larry D; Benjamin, Emelia J; Cupples, L Adrienne; D'Agostino, Ralph B; Fox, Caroline S; Govindaraju, Diddahally R; Guo, Chao-Yu; Heard-Costa, Nancy L; Hwang, Shih-Jen; Murabito, Joanne M; Newton-Cheh, Christopher; O'Donnell, Christopher J; Seshadri, Sudha; Vasan, Ramachandran S; Wang, Thomas J; Wolf, Philip A; Levy, Daniel (BioMed Central, 2007-9-19)
    BACKGROUND: Cardiovascular disease (CVD) and its most common manifestations – including coronary heart disease (CHD), stroke, heart failure (HF), and atrial fibrillation (AF) – are major causes of morbidity and mortality. ...
  • Cupples, L Adrienne; Arruda, Heather T; Benjamin, Emelia J; D'Agostino, Ralph B; Demissie, Serkalem; DeStefano, Anita L; Dupuis, Josée; Falls, Kathleen M; Fox, Caroline S; Gottlieb, Daniel J; Govindaraju, Diddahally R; Guo, Chao-Yu; Heard-Costa, Nancy L; Hwang, Shih-Jen; Kathiresan, Sekar; Kiel, Douglas P; Laramie, Jason M; Larson, Martin G; Levy, Daniel; Liu, Chun-Yu; Lunetta, Kathryn L; Mailman, Matthew D; Manning, Alisa K; Meigs, James B; Murabito, Joanne M; Newton-Cheh, Christopher; O'Connor, George T; O'Donnell, Christopher J; Pandey, Mona; Seshadri, Sudha; Vasan, Ramachandran S; Wang, Zhen Y; Wilk, Jemma B; Wolf, Philip A; Yang, Qiong; Atwood, Larry D (BioMed Central, 2007-9-19)
    BACKGROUND: The Framingham Heart Study (FHS), founded in 1948 to examine the epidemiology of cardiovascular disease, is among the most comprehensively characterized multi-generational studies in the world. Many collected ...
  • Cupples, L Adrienne; Arruda, Heather T; Benjamin, Emelia J; D'Agostino, Ralph B; Demissie, Serkalem; DeStefano, Anita L; Dupuis, Josée; Falls, Kathleen M; Fox, Caroline S; Gottlieb, Daniel J; Govindaraju, Diddahally R; Guo, Chao-Yu; Heard-Costa, Nancy L; Hwang, Shih-Jen; Kathiresan, Sekar; Kiel, Douglas P; Laramie, Jason M; Larson, Martin G; Levy, Daniel; Liu, Chun-Yu; Lunetta, Kathryn L; Mailman, Matthew D; Manning, Alisa K; Meigs, James B; Murabito, Joanne M; Newton-Cheh, Christopher; O'Connor, George T; O'Donnell, Christopher J; Pandey, Mona; Seshadri, Sudha; Vasan, Ramachandran S; Wang, Zhen Y; Wilk, Jemma B; Wolf, Philip A; Yang, Qiong; Atwood, Larry D (BioMed Central, 2007-9-19)
    BACKGROUND: The Framingham Heart Study (FHS), founded in 1948 to examine the epidemiology of cardiovascular disease, is among the most comprehensively characterized multi-generational studies in the world. Many collected ...
  • Vasan, Ramachandran S; Larson, Martin G; Aragam, Jayashri; Wang, Thomas J; Mitchell, Gary F; Kathiresan, Sekar; Newton-Cheh, Christopher; Vita, Joseph A; Keyes, Michelle J; O'Donnell, Christopher J; Levy, Daniel; Benjamin, Emelia J (BioMed Central, 2007-9-19)
    BACKGROUND: Echocardiographic left ventricular (LV) measurements, exercise responses to standardized treadmill test (ETT) and brachial artery (BA) vascular function are heritable traits that are associated with cardiovascular ...
  • Kottgen, Anna; Kao, Wen Hong L; Hwang, Shih-Jen; Boerwinkle, Eric; Yang, Qiong; Levy, Daniel; Benjamin, Emelia J; Larson, Martin G; Astor, Brad C; Coresh, Josef; Fox, Caroline S (BioMed Central, 2008-6-3)
    BACKGROUND: The Framingham Heart Study (FHS) recently obtained initial results from the first genome-wide association scan for renal traits. The study of 70,987 single nucleotide polymorphisms (SNPs) in 1,010 FHS participants ...
  • Murabito, Joanne M; Rosenberg, Carol L; Finger, Daniel; Kreger, Bernard E; Levy, Daniel; Splansky, Greta Lee; Antman, Karen; Hwang, Shih-Jen (BioMed Central, 2007-9-19)
    BACKGROUND: Breast and prostate cancer are two commonly diagnosed cancers in the United States. Prior work suggests that cancer causing genes and cancer susceptibility genes can be identified. METHODS: We conducted a ...
  • Newton-Cheh, Christopher; Guo, Chao-Yu; Wang, Thomas J; O'Donnell, Christopher J; Levy, Daniel; Larson, Martin G (BioMed Central, 2007-9-19)
    BACKGROUND: Heritable electrocardiographic (ECG) and heart rate variability (HRV) measures, reflecting pacemaking, conduction, repolarization and autonomic function in the heart have been associated with risks for cardiac ...
  • McArdle, Patrick F; Rutherford, Sue; Mitchell, Braxton D; Damcott, Coleen M; Wang, Ying; Ramachandran, Vasan; Ott, Sandy; Chang, Yen-Pei C; Levy, Daniel; Steinle, Nanette (BioMed Central, 2008-7-14)
    BACKGROUND: Systemic blood pressure, influenced by both genetic and environmental factors, is regulated via sympathetic nerve activity. We assessed the role of genetic variation in three subunits of the neuromuscular ...
  • Kimura, Masayuki; Cherkas, Lynn F; Kato, Bernet S; Demissie, Serkalem; Hjelmborg, Jacob B; Brimacombe, Michael; Cupples, Adrienne; Hunkin, Janice L; Gardner, Jefferey P; Lu, Xiaobin; Cao, Xiaojian; Sastrasinh, Malinee; Province, Michael A; Hunt, Steven C; Christensen, Kaare; Levy, Daniel; Spector, Tim D; Aviv, Abraham (Public Library of Science, 2008-2-15)
    Leukocyte telomere length (LTL) is a complex genetic trait. It shortens with age and is associated with a host of aging-related disorders. Recent studies have observed that offspring of older fathers have longer LTLs. We ...
  • Levy, Daniel; DePalma, Steven R; Benjamin, Emelia J; O'Donnell, Christopher J; Parise, Helen; Hirschhorn, Joel N; Vasan, Ramachandran S; Izumo, Seigo; Larson, Martin G (BioMed Central, 2006-5-22)
    BACKGROUND: High-throughput genotyping generates vast amounts of data for analysis; results can be difficult to summarize succinctly. A single project may involve genotyping many genes with multiple variants per gene and ...
  • Lieb, Wolfgang; Sullivan, Lisa M.; Harris, Tamara B.; Roubenoff, Ronenn; Benjamin, Emelia J.; Levy, Daniel; Fox, Caroline S.; Wang, Thomas J.; Wilson, Peter W.; Kannel, William B.; Vasan, Ramachandran S. (American Diabetes Association, 2008-12-29)
    OBJECTIVE: Obesity predisposes individuals to congestive heart failure (CHF) and cardiovascular disease (CVD). Leptin regulates energy homeostasis, is elevated in obesity, and influences ventricular and vascular remodeling. ...