Browsing by Author "Yaar, Mina"

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Browsing by Author "Yaar, Mina"

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  • Inhibition of Melanoma Angiogenesis by Telomere Homolog Oligonucleotides
    Coleman, Christina; Levine, Danielle; Kishore, Raj; Qin, Gangjian; Thorne, Tina; Lambers, Erin; Sasi, Sharath P.; Yaar, Mina; Gilchrest, Barbara A.; Goukassian, David A. (Hindawi Publishing Corporation, 2010-6-28)
    Telomere homolog oligonucleotides (T-oligos) activate an innate telomere-based program that leads to multiple anticancer effects. T-oligos act at telomeres to initiate signaling through the Werner protein and ATM kinase. ...
  • Role of BMP-4 and Its Signaling Pathways in Cultured Human Melanocytes
    Park, Hee-Young; Wu, Christina; Yaar, Mina; Stachur, Christina M.; Kosmadaki, Marita; Gilchrest, Barbara A. (Hindawi Publishing Corporation, 2009-12-30)
    Bone Morphogenetic Protein (BMP-4) was shown to down-regulate melanogenesis, in part, by decreasing the level of tyrosinase [Yaar et al. (2006) JBC:281]. Results presented here show that BMP-4 down-regulated the protein ...
  • Telomeric DNA Induces Apoptosis and Senescence of Human Breast Carcinoma Cells
    Yaar, Mina; Eller, Mark S; Panova, Izabela; Kubera, John; Wee, Lee Hng; Cowan, Kenneth H; Gilchrest, Barbara A (BioMed Central, 2007-1-26)
    INTRODUCTION. Cancer is a leading cause of death in Americans. We have identified an inducible cancer avoidance mechanism in cells that reduces mutation rate, reduces and delays carcinogenesis after carcinogen exposure, ...