Browsing SPH Biostatistics Papers by Author "Van Eerdewegh, Paul"

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Browsing SPH Biostatistics Papers by Author "Van Eerdewegh, Paul"

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  • Chen, Ming-Huei; Van Eerdewegh, Paul; Dupuis, Josée (BioMed Central, 2005-12-30)
    We applied three approaches for the identification of polymorphisms explaining the linkage evidence to the Genetic Analysis Workshop 14 simulated data: 1) the genotype-IBD sharing test (GIST); 2) an approach suggested by ...
  • Chen, Ming-Huei; Cui, Jing; Guo, Chao-Yu; Cupples, L Adrienne; Van Eerdewegh, Paul; Dupuis, Josée; Yang, Qiong (BioMed Central, 2007-12-18)
    There has been a growing interest in developing strategies for identifying single-nucleotide polymorphisms (SNPs) that explain a linkage signal by joint modeling of linkage and association. We compare several existing ...
  • Bureau, Alexandre; Dupuis, Josée; Hayward, Brooke; Falls, Kathleen; Van Eerdewegh, Paul (BioMed Central, 2003-12-31)
    Random Forest is a prediction technique based on growing trees on bootstrap samples of data, in conjunction with a random selection of explanatory variables to define the best split at each node. In the case of a quantitative ...
  • Lunetta, Kathryn L; Hayward, L Brooke; Segal, Jonathan; Van Eerdewegh, Paul (BioMed Central, 2004-12-10)
    BACKGROUND. Genome-wide association studies for complex diseases will produce genotypes on hundreds of thousands of single nucleotide polymorphisms (SNPs). A logical first approach to dealing with massive numbers of SNPs ...

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