Browsing SPH Biostatistics Papers by Author "Yang, Qiong"

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Browsing SPH Biostatistics Papers by Author "Yang, Qiong"

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  • Larson, Pamela S; Schlechter, Benjamin L; King, Chia-Lin; Yang, Qiong; Glass, Chelsea N; Mack, Charline; Pistey, Robert; de las Morenas, Antonio; Rosenberg, Carol L (BioMed Central, 2008-3-6)
    BACKGROUND. CDKN1C (also known as p57KIP2) is a cyclin-dependent kinase inhibitor previously implicated in several types of human cancer. Its family members (CDKN1A/p21CIP1 and B/p27KIP1) have been implicated in breast ...
  • Cupples, L Adrienne; Yang, Qiong; Demissie, Serkalem; Copenhafer, Donna; Levy, Daniel (BioMed Central, 2003-12-31)
  • Cupples, L Adrienne; Arruda, Heather T; Benjamin, Emelia J; D'Agostino, Ralph B; Demissie, Serkalem; DeStefano, Anita L; Dupuis, Josée; Falls, Kathleen M; Fox, Caroline S; Gottlieb, Daniel J; Govindaraju, Diddahally R; Guo, Chao-Yu; Heard-Costa, Nancy L; Hwang, Shih-Jen; Kathiresan, Sekar; Kiel, Douglas P; Laramie, Jason M; Larson, Martin G; Levy, Daniel; Liu, Chun-Yu; Lunetta, Kathryn L; Mailman, Matthew D; Manning, Alisa K; Meigs, James B; Murabito, Joanne M; Newton-Cheh, Christopher; O'Connor, George T; O'Donnell, Christopher J; Pandey, Mona; Seshadri, Sudha; Vasan, Ramachandran S; Wang, Zhen Y; Wilk, Jemma B; Wolf, Philip A; Yang, Qiong; Atwood, Larry D (BioMed Central, 2007-9-19)
    BACKGROUND: The Framingham Heart Study (FHS), founded in 1948 to examine the epidemiology of cardiovascular disease, is among the most comprehensively characterized multi-generational studies in the world. Many collected ...
  • Yang, Qiong; Chazaro, Irmarie; Cui, Jing; Guo, Chao-Yu; Demissie, Serkalem; Larson, Martin; Atwood, Larry D; Cupples, L Adrienne; DeStefano, Anita L (BioMed Central, 2003-12-31)
    BACKGROUND. We explored three approaches to heritability and linkage analyses of longitudinal total cholesterol levels (CHOL) in the Genetic Analysis Workshop 13 simulated data without knowing the answers. The first two ...
  • Cordell, Heather J; de Andrade, Mariza; Babron, Marie-Claude; Bartlett, Christopher W; Beyene, Joseph; Bickeböller, Heike; Culverhouse, Robert; Cupples, L Adrienne; Daw, E Warwick; Dupuis, Josée; Falk, Catherine T; Ghosh, Saurabh; Goddard, Katrina A; Goode, Ellen L; Hauser, Elizabeth R; Martin, Lisa J; Martinez, Maria; North, Kari E; Saccone, Nancy L; Schmidt, Silke; Tapper, William; Thomas, Duncan; Tritchler, David; Vieland, Veronica J; Wijsman, Ellen M; Wilcox, Marsha A; Witte, John S; Yang, Qiong; Ziegler, Andreas; Almasy, Laura; MacCluer, Jean W (BioMed Central, 2007-12-18)
  • Yang, Qiong; Kathiresan, Sekar; Lin, Jing-Ping; Tofler, Geoffrey H; O'Donnell, Christopher J (BioMed Central, 2007-9-19)
    BACKGROUND: Increased circulating levels of hemostatic factors as well as anemia have been associated with increased risk of cardiovascular disease (CVD). Known associations between hemostatic factors and sequence variants ...
  • Hwang, Shih-Jen; Yang, Qiong; Meigs, James B; Pearce, Elizabeth N; Fox, Caroline S (BioMed Central, 2007-9-19)
    BACKGROUND: Glomerular filtration rate (GFR) and urinary albumin excretion (UAE) are markers of kidney function that are known to be heritable. Many endocrine conditions have strong familial components. We tested for ...
  • Meyer, Tamra E.; Verwoert, Germaine C.; Hwang, Shih-Jen; Glazer, Nicole L.; Smith, Albert V.; van Rooij, Frank J. A.; Ehret, Georg B.; Boerwinkle, Eric; Felix, Janine F.; Leak, Tennille S.; Harris, Tamara B.; Yang, Qiong; Dehghan, Abbas; Aspelund, Thor; Katz, Ronit; Homuth, Georg; Kocher, Thomas; Rettig, Rainer; Ried, Janina S.; Gieger, Christian; Prucha, Hanna; Pfeufer, Arne; Meitinger, Thomas; Coresh, Josef; Hofman, Albert; Sarnak, Mark J.; Chen, Yii-Der Ida; Uitterlinden, André G.; Chakravarti, Aravinda; Psaty, Bruce M.; van Duijn, Cornelia M.; Kao, W. H. Linda; Witteman, Jacqueline C. M.; Gudnason, Vilmundur; Siscovick, David S.; Fox, Caroline S.; Köttgen, Anna (Public Library of Science, 2010-8-5)
    Magnesium, potassium, and sodium, cations commonly measured in serum, are involved in many physiological processes including energy metabolism, nerve and muscle function, signal transduction, and fluid and blood pressure ...
  • Kottgen, Anna; Kao, Wen Hong L; Hwang, Shih-Jen; Boerwinkle, Eric; Yang, Qiong; Levy, Daniel; Benjamin, Emelia J; Larson, Martin G; Astor, Brad C; Coresh, Josef; Fox, Caroline S (BioMed Central, 2008-6-3)
    BACKGROUND: The Framingham Heart Study (FHS) recently obtained initial results from the first genome-wide association scan for renal traits. The study of 70,987 single nucleotide polymorphisms (SNPs) in 1,010 FHS participants ...
  • Cho, Kelly; Yang, Qiong; Dupuis, Josée (BioMed Central, 2007-12-18)
    The presence of linkage disequilibrium violates the underlying assumption of linkage equilibrium in most traditional multipoint linkage approaches. Studies have shown that such violation leads to bias in qualitative trait ...
  • Chen, Ming-Huei; Cui, Jing; Guo, Chao-Yu; Cupples, L Adrienne; Van Eerdewegh, Paul; Dupuis, Josée; Yang, Qiong (BioMed Central, 2007-12-18)
    There has been a growing interest in developing strategies for identifying single-nucleotide polymorphisms (SNPs) that explain a linkage signal by joint modeling of linkage and association. We compare several existing ...
  • Yang, Qiong; Cui, Jing; Chazaro, Irmarie; Cupples, L Adrienne; Demissie, Serkalem (BioMed Central, 2005-12-30)
    In genome-wide genetic studies with a large number of markers, balancing the type I error rate and power is a challenging issue. Recently proposed false discovery rate (FDR) approaches are promising solutions to this ...
  • Chen, Ming-Huei; Larson, Martin G; Hsu, Yi-Hsiang; Peloso, Gina M; Guo, Chao-Yu; Fox, Caroline S; Atwood, Larry D; Yang, Qiong (BioMed Central, 2010-5-14)
    BACKGROUND. Genome-wide association (GWA) studies that use population-based association approaches may identify spurious associations in the presence of population admixture. In this paper, we propose a novel three-stage ...
  • Meng, Yan; Yang, Qiong; Cuenco, Karen T; Cupples, L Adrienne; DeStefano, Anita L; Lunetta, Kathryn L (BioMed Central, 2007-12-18)
    We used the simulated data set from Genetic Analysis Workshop 15 Problem 3 to assess a two-stage approach for identifying single-nucleotide polymorphisms (SNPs) associated with rheumatoid arthritis (RA). In the first stage, ...

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