Late onset of huntington's disease

dc.contributor.author	Myers, R.H.
dc.contributor.author	Sax, D.S.
dc.contributor.author	Schoenfeld, M
dc.contributor.author	Bird, E.D.
dc.contributor.author	Wolf, P.A.
dc.contributor.author	Vonsattel, J.P.
dc.contributor.author	White, R.F.
dc.contributor.author	Martin, J.B.
dc.date.accessioned	2009-10-17T14:48:16Z
dc.date.available	2009-10-17T14:48:16Z
dc.date.issued	1985
dc.identifier.citation	Myers, R. H., Sax, D. S., Schoenfeld, M., Bird, E. D., Wolf, P. A., Vonsattel, J. P., White, R. F., & Martin, J. B. (1985). Late onset of huntington's disease. Journal of Neurology, Neurosurgery, and Psychiatry, 48(6), 530-534.	en_US
dc.identifier.uri	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1028368/?tool=pmcentrez	en_US
dc.identifier.uri	http://hdl.handle.net/2144/1208
dc.description.abstract	Twenty-five patients with late-onset Huntington's disease were studied; motor impairment appeared at age 50 years or later. The average age at onset of chorea was 57.5 years, with an average age at diagnosis of 63.1 years. Approximately 25% of persons affected by Huntington's disease exhibit late onset. A preponderance of maternal transmission was noted in late-onset Huntington's disease. The clinical features resembled those of mid-life onset Huntington's disease but progressed more slowly. Neuropathological evaluation of two cases reveal less severe neuronal atrophy than for mid-life onset disease.	en_US
dc.publisher	BMJ Publishing Group	en_US
dc.title	Late onset of huntington's disease	en_US
dc.type	Article	en_US