- OpenBU
- →
- College of Engineering
- →
- Bioinformatics
- →
- ENG: Bioinformatics: Scholarly Papers
- →
- Browsing ENG: Bioinformatics: Scholarly Papers by Title
JavaScript is disabled for your browser. Some features of this site may not work without it.
Browsing ENG: Bioinformatics: Scholarly Papers by Title
Now showing items 41-60 of 100
-
(BioMed Central, 2008-2-25)BACKGROUND. Information obtained from diverse data sources can be combined in a principled manner using various machine learning methods to increase the reliability and range of knowledge about protein function. The result ...
-
(Public Library of Science, 2007-8-17)The identification of regulatory elements from different cell types is necessary for understanding the mechanisms controlling cell type–specific and housekeeping gene expression. Mapping DNaseI hypersensitive (HS) sites ...
-
(Libertas Academica, 2007-2-9)Microarray gene expression profiling has been used to distinguish histological subtypes of renal cell carcinoma (RCC), and consequently to identify specific tumor markers. The analytical procedures currently in use find ...
-
(BioMed Central, 2010-02-26)A gene set enrichment analysis method for including network topology in the identification of genes involved in phenotypic alterations is described. One of the important challenges to post-genomic biology is relating ...
-
(Public Library of Science, 2005-6-24)Understanding the relationship between protein structure and function is one of the foremost challenges in post-genomic biology. Higher conservation of structure could, in principle, allow researchers to extend current ...
-
(BioMed Central, 2008-02-25)A report of the 6th Georgia Tech-Oak Ridge National Lab International Conference on Bioinformatics 'In silico Biology: Gene Discovery and Systems Genomics', Atlanta, USA, 15-17 November, 2007.
-
(BioMed Central, 2008-6-18)BACKGROUND. An important goal in bioinformatics is to unravel the network of transcription factors (TFs) and their targets. This is important in the human genome, where many TFs are involved in disease progression. Here, ...
-
(Public Library of Science, 2008-7-25)Chromatin structure plays an important role in modulating the accessibility of genomic DNA to regulatory proteins in eukaryotic cells. We performed an integrative analysis on dozens of recent datasets generated by ...
-
(Public Library of Science, 2009-6-12)Rates of evolution differ widely among proteins, but the causes and consequences of such differences remain under debate. With the advent of high-throughput functional genomics, it is now possible to rigorously assess the ...
-
(BioMed Central, 2008-8-22)BACKGROUND. In the current climate of high-throughput computational biology, the inference of a protein's function from related measurements, such as protein-protein interaction relations, has become a canonical task. Most ...
-
(BioMed Central, 2006-6-8)A systematic curation of the literature on Saccharomyces cerevisiae has yielded a comprehensive collection of experimentally observed interactions. This new resource augments current views of the topological structure of ...
-
(Nature Publishing Group, 2009-08-18)In the past decade, computational methods have been shown to be well suited to unraveling the complex web of metabolic reactions in biological systems. Methods based on flux–balance analysis (FBA) and bi-level optimization ...
-
(Public Library of Science, 2007-1-9)Machine learning approaches offer the potential to systematically identify transcriptional regulatory interactions from a compendium of microarray expression profiles. However, experimental validation of the performance ...
-
(BioMed Central, 2007-09-10)The LeFE algorithm has been developed to address the complex, non-linear regulation of gene expression. Interpretation of microarray data remains a challenge, and most methods fail to consider the complex, nonlinear ...
-
(BioMed Central, 2007-9-18)BACKGROUND. Lightweight genome viewer (lwgv) is a web-based tool for visualization of sequence annotations in their chromosomal context. It performs most of the functions of larger genome browsers, while relying on standard ...
-
(Kluwer Academic Publishers, 2006-10-31)High throughput technologies, including array-based chromatin immunoprecipitation, have rapidly increased our knowledge of transcriptional maps-the identity and location of regulatory binding sites within genomes. Still, ...
-
(Oxford University Press, 2008-1)Many Microbe Microarrays Database (M3D) is designed to facilitate the analysis and visualization of expression data in compendia compiled from multiple laboratories. M3D contains over a thousand Affymetrix microarrays for ...
-
(Oxford University Press, 2010-01-04)Initiation and regulation of gene expression is critically dependent on the binding of transcriptional regulators, which is often temporal and position specific. Many transcriptional regulators recognize and bind specific ...
-
(BioMed Central, 2008-09-22)An iterative approach that integrates high-throughput measurements of yeast deletion mutants and flux balance model predictions improves understanding of both experimental and computational results. BACKGROUND. Understanding ...
-
(BioMed Central, 2005-12-30)Complex diseases are generally thought to be under the influence of multiple, and possibly interacting, genes. Many association methods have been developed to identify susceptibility genes assuming a single-gene disease ...
Now showing items 41-60 of 100
