Telomere homolog oligonucleotides (T-oligos) activate an innate telomere-based program that leads to multiple anticancer effects. T-oligos act at telomeres to initiate signaling through the Werner protein and ATM kinase. ...
Park, Hee-Young; Wu, Christina; Yaar, Mina; Stachur, Christina M.; Kosmadaki, Marita; Gilchrest, Barbara A.(Hindawi Publishing Corporation, 2009-12-30)
Bone Morphogenetic Protein (BMP-4) was shown to down-regulate melanogenesis, in part, by decreasing the level of tyrosinase [Yaar et al. (2006) JBC:281]. Results presented here show that BMP-4 down-regulated the protein ...
