Lifetime Risk of Cardiovascular Disease Among Individuals With and Without Diabetes Stratified by Obesity Status in the Framingham Heart Study

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dc.contributor.author Fox, Caroline S. en_US
dc.contributor.author Pencina, Michael J. en_US
dc.contributor.author Wilson, Peter W.F. en_US
dc.contributor.author Paynter, Nina P. en_US
dc.contributor.author Vasan, Ramachandran S. en_US
dc.contributor.author D'Agostino, Ralph B. en_US
dc.date.accessioned 2011-12-29T21:03:22Z
dc.date.available 2011-12-29T21:03:22Z
dc.date.issued 2011-12-29
dc.identifier.citation Fox, Caroline S., Michael J. Pencina, Peter W.F. Wilson, Nina P. Paynter, Ramachandran S. Vasan, Ralph B. D'Agostino. "Lifetime Risk of Cardiovascular Disease Among Individuals With and Without Diabetes Stratified by Obesity Status in the Framingham Heart Study " Diabetes Care 31(8): 1582-1584. (2008) en_US
dc.identifier.issn 1935-5548 en_US
dc.identifier.uri http://hdl.handle.net/2144/2547
dc.description.abstract OBJECTIVE: We assessed the lifetime risk of cardiovascular disease (CVD) among individuals with and without obesity and diabetes. RESEARCH DESIGN AND METHODS: Participants were drawn from the original and offspring cohorts of the Framingham Heart Study. Lifetime (30-year) risk of CVD was assessed using a modified Kaplan-Meier approach adjusting for the competing risk of death, beginning from age 50 years. RESULTS: Over 30 years, the lifetime risk of CVD among women with diabetes was 54.8% among normal-weight women and 78.8% among obese women. Among normal-weight men with diabetes, the lifetime risk of CVD was 78.6%, whereas it was 86.9% among obese men. CONCLUSIONS: The lifetime risk of CVD among individuals with diabetes is high, and this relationship is further accentuated with increasing adiposity. en_US
dc.description.sponsorship National Institutes of Health National Heart, Lung and Blood Institute’s Framingham Heart Study (N01-HC-25195); National Institutes of Health (K24 HL04334) en_US
dc.language.iso en en_US
dc.publisher American Diabetes Association en_US
dc.rights Copyright 2008, American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details. en_US
dc.title Lifetime Risk of Cardiovascular Disease Among Individuals With and Without Diabetes Stratified by Obesity Status in the Framingham Heart Study en_US
dc.type article en_US
dc.identifier.doi 10.2337/dc08-0025 en_US
dc.identifier.pubmedid 18458146 en_US
dc.identifier.pmcid 2494632 en_US

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