Burden of Malaria in Pregnancy in Jharkhand State, India


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dc.contributor.author Hamer, Davidson H en_US
dc.contributor.author Singh, Mrigendra P en_US
dc.contributor.author Wylie, Blair J en_US
dc.contributor.author Yeboah-Antwi, Kojo en_US
dc.contributor.author Tuchman, Jordan en_US
dc.contributor.author Desai, Meghna en_US
dc.contributor.author Udhayakumar, Venkatachalam en_US
dc.contributor.author Gupta, Priti en_US
dc.contributor.author Brooks, Mohamad I en_US
dc.contributor.author Shukla, Manmohan M en_US
dc.contributor.author Awasthy, Kiran en_US
dc.contributor.author Sabin, Lora en_US
dc.contributor.author MacLeod, William B en_US
dc.contributor.author Dash, Aditya P en_US
dc.contributor.author Singh, Neeru en_US
dc.date.accessioned 2012-01-09T20:58:40Z
dc.date.available 2012-01-09T20:58:40Z
dc.date.copyright 2009 en_US
dc.date.issued 2009-9-3 en_US
dc.identifier.citation Hamer, Davidson H, Mrigendra P Singh, Blair J Wylie, Kojo Yeboah-Antwi, Jordan Tuchman, Meghna Desai, Venkatachalam Udhayakumar, Priti Gupta, Mohamad I Brooks, Manmohan M Shukla, Kiran Awasthy, Lora Sabin, William B MacLeod, Aditya P Dash, Neeru Singh. "Burden of malaria in pregnancy in Jharkhand State, India" Malaria Journal 8:210. (2009) en_US
dc.identifier.issn 1475-2875 en_US
dc.identifier.uri http://hdl.handle.net/2144/2948
dc.description.abstract BACKGROUND. Past studies in India included only symptomatic pregnant women and thus may have overestimated the proportion of women with malaria. Given the large population at risk, a cross sectional study was conducted in order to better define the burden of malaria in pregnancy in Jharkhand, a malaria-endemic state in central-east India. METHODS Cross-sectional surveys at antenatal clinics and delivery units were performed over a 12-month period at two district hospitals in urban and semi-urban areas, and a rural mission hospital. Malaria was diagnosed by Giemsa-stained blood smear and/or rapid diagnostic test using peripheral or placental blood. RESULTS 2,386 pregnant women were enrolled at the antenatal clinics and 718 at the delivery units. 1.8% (43/2382) of the antenatal clinic cohort had a positive diagnostic test for malaria (53.5% Plasmodium falciparum, 37.2% Plasmodium vivax, and 9.3% mixed infections). Peripheral parasitaemia was more common in pregnant women attending antenatal clinics in rural sites (adjusted relative risk [aRR] 4.31, 95%CI 1.84-10.11) and in those who were younger than 20 years (aRR 2.68, 95%CI 1.03-6.98). Among delivery unit participants, 1.7% (12/717) had peripheral parasitaemia and 2.4% (17/712) had placental parasitaemia. Women attending delivery units were more likely to be parasitaemic if they were in their first or second pregnancy (aRR 3.17, 95%CI 1.32-7.61), had fever in the last week (aRR 5.34, 95%CI 2.89-9.90), or had rural residence (aRR 3.10, 95%CI 1.66-5.79). Malaria control measures including indoor residual spraying (IRS) and untreated bed nets were common, whereas insecticide-treated bed nets (ITN) and malaria chemoprophylaxis were rarely used. CONCLUSION The prevalence of malaria among pregnant women was relatively low. However, given the large at-risk population in this malaria-endemic region of India, there is a need to enhance ITN availability and use for prevention of malaria in pregnancy, and to improve case management of symptomatic pregnant women. en_US
dc.description.sponsorship The United States Agency for International Development (9GHS-A-00-03-00020-00); Child and Family Applied Research project at Boston University en_US
dc.language.iso en en_US
dc.publisher BioMed Central en_US
dc.rights Copyright 2009 Hamer et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. en_US
dc.rights.uri http://creativecommons.org/licenses/by/2.0 en_US
dc.title Burden of Malaria in Pregnancy in Jharkhand State, India en_US
dc.type article en_US
dc.identifier.doi 10.1186/1475-2875-8-210 en_US
dc.identifier.pubmedid 19728882 en_US
dc.identifier.pmcid 2744702 en_US

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