Upgrades to StellaBase Facilitate Medical and Genetic Studies on the Starlet Sea Anemone, Nematostella Vectensis


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dc.contributor.author Sullivan, James C. en_US
dc.contributor.author Reitzel, Adam M. en_US
dc.contributor.author Finnerty, John R. en_US
dc.date.accessioned 2012-01-11T16:53:52Z
dc.date.available 2012-01-11T16:53:52Z
dc.date.issued 2008-1 en_US
dc.identifier.citation Authors. "Upgrades to StellaBase facilitate medical and genetic studies on the starlet sea anemone, Nematostella vectensis" Nucleic Acids Research36(Database issue): D607-D611. (2008) en_US
dc.identifier.issn 1362-4962 en_US
dc.identifier.uri http://hdl.handle.net/2144/3129
dc.description.abstract The starlet sea anemone, Nematostella vectensis, is a basal metazoan organism that has recently emerged as an important model system in developmental biology and evolutionary genomics. StellaBase, the Nematostella Genomics Database (http://stellabase.org), was developed in 2005 as a resource to support the Nematostella research community. Recently, it has become apparent that Nematostella may be a particularly useful system for studying (i) microevolutionary variation in natural populations, and (ii) the functional evolution of human disease genes. We have developed two new databases that will foster such studies: StellaBase Disease (http://stellabase.org/disease) is a relational database that houses 155 904 invertebrate homologous isoforms of human disease genes from four leading genomic model systems (fly, worm, yeast and Nematostella), including 14 874 predicted genes from the sea anemone itself. StellaBase SNP (http://stellabase.org/SNP) is a relational database that describes the location and underlying type of mutation for 20 063 single nucleotide polymorphisms. en_US
dc.description.sponsorship National Science Foundation (FP-91656101-0); Environmental Protectment Agency (F5E11155); Woods Hole Oceanographic Institution; The Beacon Institute for Rivers and Estuaries; J. Seward Johnson Fund en_US
dc.language.iso en en_US
dc.publisher Nucleic Acids Research en_US
dc.title Upgrades to StellaBase Facilitate Medical and Genetic Studies on the Starlet Sea Anemone, Nematostella Vectensis en_US
dc.type article en_US
dc.identifier.doi 10.1093/nar/gkm941 en_US
dc.identifier.pubmedid 17982171 en_US
dc.identifier.pmcid 2238866 en_US

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