Exploring the Relationship between Chronic Undernutrition and Asymptomatic Malaria in Ghanaian Children


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dc.contributor.author Crookston, Benjamin T en_US
dc.contributor.author Alder, Stephen C en_US
dc.contributor.author Boakye, Isaac en_US
dc.contributor.author Merrill, Ray M en_US
dc.contributor.author Amuasi, John H en_US
dc.contributor.author Porucznik, Christina A en_US
dc.contributor.author Stanford, Joseph B en_US
dc.contributor.author Dickerson, Ty T en_US
dc.contributor.author Dearden, Kirk A en_US
dc.contributor.author Hale, DeVon C en_US
dc.contributor.author Sylverken, Justice en_US
dc.contributor.author Snow, Bryce S en_US
dc.contributor.author Osei-Akoto, Alex en_US
dc.contributor.author Ansong, Daniel en_US
dc.date.accessioned 2012-01-11T21:43:53Z
dc.date.available 2012-01-11T21:43:53Z
dc.date.copyright 2010 en_US
dc.date.issued 2010-2-2 en_US
dc.identifier.citation Crookston, Benjamin T, Stephen C Alder, Isaac Boakye, Ray M Merrill, John H Amuasi, Christina A Porucznik, Joseph B Stanford, Ty T Dickerson, Kirk A Dearden, DeVon C Hale, Justice Sylverken, Bryce S Snow, Alex Osei-Akoto, Daniel Ansong. "Exploring the relationship between chronic undernutrition and asymptomatic malaria in Ghanaian children" Malaria Journal 9:39. (2010) en_US
dc.identifier.issn 1475-2875 en_US
dc.identifier.uri http://hdl.handle.net/2144/3241
dc.description.abstract BACKGROUND A moderate association has been found between asymptomatic parasitaemia and undernutrition. However, additional investigation using the gold standard for asymptomatic parasitaemia confirmation, polymerase chain reaction (PCR), is needed to validate this association. Anthropometric measurements and blood samples from children less than five years of age in a rural Ghanaian community were used to determine if an association exists between chronic undernutrition and PCR-confirmed cases of asymptomatic malaria. METHODS This was a descriptive cross-sectional study of 214 children less than five years of age from a community near Kumasi, Ghana. Blood samples and anthropometric measurements from these children were collected during physical examinations conducted in January 2007 by partners of the Barekuma Collaborative Community Development Programme. RESULTS Findings from the logistic model predicting the odds of asymptomatic malaria indicate that children who experienced mild, moderate or severe stunting were not more likely to have asymptomatic malaria than children who were not stunted. Children experiencing anaemia had an increased likelihood (OR = 4.15; 95% CI: 1.92, 8.98) of asymptomatic malaria. Similarly, increased spleen size, which was measured by ultrasound, was also associated with asymptomatic malaria (OR = 2.17; 95% CI: 1.44, 3.28). Fast breathing, sex of the child, and age of the child were not significantly associated with the asymptomatic malaria. CONCLUSIONS No significant association between chronic undernutrition and presence of asymptomatic malaria was found. Children who experience anaemia and children who have splenomegaly are more likely to present asymptomatic malaria. Programmes aimed at addressing malaria should continue to include nutritional components, especially components that address anaemia. en_US
dc.description.sponsorship University of Utah en_US
dc.language.iso en en_US
dc.publisher BioMed Central en_US
dc.rights Copyright 2010 Crookston et al; licensee BioMed Central Ltd. en_US
dc.rights.uri http://creativecommons.org/licenses/by/2.0 en_US
dc.title Exploring the Relationship between Chronic Undernutrition and Asymptomatic Malaria in Ghanaian Children en_US
dc.type article en_US
dc.identifier.doi 10.1186/1475-2875-9-39 en_US
dc.identifier.pubmedid 20122258 en_US
dc.identifier.pmcid 2837055 en_US

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