Browsing College of Arts and Sciences by Author "Guo, Chao-Yu"

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Browsing College of Arts and Sciences by Author "Guo, Chao-Yu"

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  • Larson, Martin G; Atwood, Larry D; Benjamin, Emelia J; Cupples, L Adrienne; D'Agostino, Ralph B; Fox, Caroline S; Govindaraju, Diddahally R; Guo, Chao-Yu; Heard-Costa, Nancy L; Hwang, Shih-Jen; Murabito, Joanne M; Newton-Cheh, Christopher; O'Donnell, Christopher J; Seshadri, Sudha; Vasan, Ramachandran S; Wang, Thomas J; Wolf, Philip A; Levy, Daniel (BioMed Central, 2007-9-19)
    BACKGROUND: Cardiovascular disease (CVD) and its most common manifestations – including coronary heart disease (CHD), stroke, heart failure (HF), and atrial fibrillation (AF) – are major causes of morbidity and mortality. ...
  • Larson, Martin; Atwood, Larry; Benjamin, Emelia; Cupples, L Adrienne; D'Agostino, Ralph; Fox, Caroline; Govindaraju, Diddahally; Guo, Chao-Yu; Heard-Costa, Nancy; Hwang, Shih-Jen; et al. (2007)
    BACKGROUND:Cardiovascular disease (CVD) and its most common manifestations - including coronary heart disease (CHD), stroke, heart failure (HF), and atrial fibrillation (AF) - are major causes of morbidity ...
  • Cupples, L Adrienne; Arruda, Heather T; Benjamin, Emelia J; D'Agostino, Ralph B; Demissie, Serkalem; DeStefano, Anita L; Dupuis, Josée; Falls, Kathleen M; Fox, Caroline S; Gottlieb, Daniel J; Govindaraju, Diddahally R; Guo, Chao-Yu; Heard-Costa, Nancy L; Hwang, Shih-Jen; Kathiresan, Sekar; Kiel, Douglas P; Laramie, Jason M; Larson, Martin G; Levy, Daniel; Liu, Chun-Yu; Lunetta, Kathryn L; Mailman, Matthew D; Manning, Alisa K; Meigs, James B; Murabito, Joanne M; Newton-Cheh, Christopher; O'Connor, George T; O'Donnell, Christopher J; Pandey, Mona; Seshadri, Sudha; Vasan, Ramachandran S; Wang, Zhen Y; Wilk, Jemma B; Wolf, Philip A; Yang, Qiong; Atwood, Larry D (BioMed Central, 2007-9-19)
    BACKGROUND: The Framingham Heart Study (FHS), founded in 1948 to examine the epidemiology of cardiovascular disease, is among the most comprehensively characterized multi-generational studies in the world. Many collected ...
  • Yang, Qiong; Chazaro, Irmarie; Cui, Jing; Guo, Chao-Yu; Demissie, Serkalem; Larson, Martin; Atwood, Larry D; Cupples, L Adrienne; DeStefano, Anita L (BioMed Central, 2003-12-31)
    BACKGROUND. We explored three approaches to heritability and linkage analyses of longitudinal total cholesterol levels (CHOL) in the Genetic Analysis Workshop 13 simulated data without knowing the answers. The first two ...
  • Lunetta, Kathryn L; D'Agostino, Ralph B; Karasik, David; Benjamin, Emelia J; Guo, Chao-Yu; Govindaraju, Raju; Kiel, Douglas P; Kelly-Hayes, Margaret; Massaro, Joseph M; Pencina, Michael J; Seshadri, Sudha; Murabito, Joanne M (BioMed Central, 2007-9-19)
    BACKGROUND: Family studies and heritability estimates provide evidence for a genetic contribution to variation in the human life span. METHODS: We conducted a genome wide association study (Affymetrix 100K SNP GeneChip) ...
  • Newton-Cheh, Christopher; Guo, Chao-Yu; Wang, Thomas J; O'Donnell, Christopher J; Levy, Daniel; Larson, Martin G (BioMed Central, 2007-9-19)
    BACKGROUND: Heritable electrocardiographic (ECG) and heart rate variability (HRV) measures, reflecting pacemaking, conduction, repolarization and autonomic function in the heart have been associated with risks for cardiac ...
  • Guo, Chao-Yu (BioMed Central, 2007-12-18)
    The transmission/disequilibrium test was introduced to test for linkage and association between a marker and a putative disease locus using case-parent triads. Several extensions have been proposed to accommodate incomplete ...
  • Guo, Chao-Yu; Cui, Jing; Cupples, L Adrienne (BioMed Central, 2005-12-30)
    The transmission/disequilibrium test was introduced to test for linkage disequilibrium between a marker and a putative disease locus using case-parent trios. However, parental genotypes may be incomplete in such a study. ...
  • Chen, Ming-Huei; Cui, Jing; Guo, Chao-Yu; Cupples, L Adrienne; Van Eerdewegh, Paul; Dupuis, Josée; Yang, Qiong (BioMed Central, 2007-12-18)
    There has been a growing interest in developing strategies for identifying single-nucleotide polymorphisms (SNPs) that explain a linkage signal by joint modeling of linkage and association. We compare several existing ...
  • Chen, Ming-Huei; Larson, Martin G; Hsu, Yi-Hsiang; Peloso, Gina M; Guo, Chao-Yu; Fox, Caroline S; Atwood, Larry D; Yang, Qiong (BioMed Central, 2010-5-14)
    BACKGROUND. Genome-wide association (GWA) studies that use population-based association approaches may identify spurious associations in the presence of population admixture. In this paper, we propose a novel three-stage ...

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