Browsing College of Arts and Sciences by Author "Schaffer, Michael E"

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Phosphatidylinositol 3-Kinase Signaling in Proliferating Cells Maintains an Anti-Apoptotic Transcriptional Program Mediated by Inhibition of Foxo and Non-Canonical Activation of NFkB Transcription Factors

Terragni, Jolyon; Graham, Julie R; Adams, Kenneth W; Schaffer, Michael E; Tullai, John W; Cooper, Geoffrey M (BioMed Central, 2008-1-28)

BACKGROUND. Phosphatidylinositol (PI) 3-kinase is activated by a variety of growth factor receptors and the PI 3-kinase/Akt signaling pathway is a key regulator of cell proliferation and survival. The downstream targets ...

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