Browsing College of Arts and Sciences by Author "Van Eerdewegh, Paul"

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Identification of Polymorphisms Explaining a Linkage Signal: Application to the GAW14 Simulated Data

Chen, Ming-Huei; Van Eerdewegh, Paul; Dupuis, Josée (BioMed Central, 2005-12-30)

We applied three approaches for the identification of polymorphisms explaining the linkage evidence to the Genetic Analysis Workshop 14 simulated data: 1) the genotype-IBD sharing test (GIST); 2) an approach suggested by ...
Joint Modeling of Linkage and Association Using Affected Sib-Pair Data

Chen, Ming-Huei; Cui, Jing; Guo, Chao-Yu; Cupples, L Adrienne; Van Eerdewegh, Paul; Dupuis, Josée; Yang, Qiong (BioMed Central, 2007-12-18)

There has been a growing interest in developing strategies for identifying single-nucleotide polymorphisms (SNPs) that explain a linkage signal by joint modeling of linkage and association. We compare several existing ...

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