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  • Microarray Gene Expression Profiling and Analysis in Renal Cell Carcinoma
    Liou, Louis S; Shi, Ting; Duan, Zhong-Hui; Sadhukhan, Provash; Der, Sandy D; Novick, Andrew A; Hissong, John; Skacel, Marek; Almasan, Alexandru; DiDonato, Joseph A (BioMed Central, 2004-6-22)
    BACKGROUND. Renal cell carcinoma (RCC) is the most common cancer in adult kidney. The accuracy of current diagnosis and prognosis of the disease and the effectiveness of the treatment for the disease are limited by the ...
  • Migraine and Risk of Haemorrhagic Stroke in Women: Prospective Cohort Study
    Kurth, Tobias; Kase, Carlos S; Schürks, Markus; Tzourio, Christophe; Buring, Julie E (BMJ Publishing Group Ltd., 2010-8-24)
    Objectives To examine the association between migraine and migraine aura status with risk of haemorrhagic stroke. Design Prospective cohort study. Setting Women's Health Study, United States. Participants 27860 women aged ...
  • Migraine, Fibromyalgia, and Depression among People with IBS: A Prevalence Study
    Cole, J Alexander; Rothman, Kenneth J; Cabral, Howard J; Zhang, Yuqing; Farraye, Francis A (BioMed Central, 2006-9-28)
    BACKGROUND. Case descriptions suggest IBS patients are more likely to have other disorders, including migraine, fibromyalgia, and depression. We sought to examine the prevalence of these conditions in cohorts of people ...
  • Minimal and Direct Access Surgery in Urology
    Repassy, D. L.; Frang, D.; Jako, G. J. (Hindawi Publishing Corporation, 2011-12-29)
    An alternative method to laparoscopic surgery has been developed for urological procedures. The surgery is minimal access because the length of the single skin incision ranges from 3–6 cm depending on the type of operation. ...
  • Mitochondrial Networking Protects β-Cells From Nutrient-Induced Apoptosis
    Molina, Anthony J.A.; Wikstrom, Jakob D.; Stiles, Linsey; Las, Guy; Mohamed, Hibo; Elorza, Alvaro; Walzer, Gil; Twig, Gilad; Katz, Steve; Corkey, Barbara E.; Shirihai, Orian S. (American Diabetes Association, 2009-7-6)
    OBJECTIVE: Previous studies have reported that β-cell mitochondria exist as discrete organelles that exhibit heterogeneous bioenergetic capacity. To date, networking activity, and its role in mediating β-cell mitochondrial ...
  • A Model for Transient Oxygen Delivery in Cerebral Cortex
    Ress, David; Thompson, Jeffrey K.; Rokers, Bas; Khan, Reswanul K.; Huk, Alexander C. (Frontiers Research Foundation, 2009-06-29)
    Popular hemodynamic brain imaging methods, such as blood oxygen-level dependent functional magnetic resonance imaging (BOLD fMRI), would benefit from a detailed understanding of the mechanisms by which oxygen is delivered ...
  • Modifying Effects of the HFE Polymorphisms on the Association between Lead Burden and Cognitive Decline
    Wang, Florence T.; Hu, Howard; Schwartz, Joel; Weuve, Jennifer; Spiro, Avron S.; Sparrow, David; Nie, Huiling; Silverman, Edwin K.; Weiss, Scott T.; Wright, Robert O. (National Institute of Environmental Health Sciences, 2007-08)
    BACKGROUND. As iron and lead promote oxidative damage, and hemochromatosis (HFE) gene polymorphisms increase body iron burden, HFE variant alleles may modify the lead burden and cognitive decline relationship. OBJECTIVE. ...
  • Modulation of Adipocyte Lipogenesis by Octanoate: Involvement of Reactive Oxygen Species
    Guo, Wen; Xie, Weisheng; Han, Jianrong (BioMed Central, 2006-7-27)
    BACKGROUND. Octanoate is a medium-chain fatty acid (MCFA) that is rich in milk and tropical dietary lipids. It also accounts for 70% of the fatty acids in commercial medium chain triglycerides (MCT). Use of MCT for weight ...
  • Modulators of Cytoskeletal Reorganization in CA1 Hippocampal Neurons Show Increased Expression in Patients at Mid-Stage Alzheimer's Disease
    Kao, Patricia F.; Davis, David A.; Banigan, Meredith G.; Vanderburg, Charles R.; Seshadri, Sudha; Delalle, Ivana (Public Library of Science, 2010-10-13)
    During the progression of Alzheimer's disease (AD), hippocampal neurons undergo cytoskeletal reorganization, resulting in degenerative as well as regenerative changes. As neurofibrillary tangles form and dystrophic neurites ...
  • Molecular Model of the Microvillar Cytoskeleton and Organization of the Brush Border
    Brown, Jeffrey W.; McKnight, C. James (Public Library of Science, 2010-2-24)
    BACKGROUND. Brush border microvilli are ~1-µm long finger-like projections emanating from the apical surfaces of certain, specialized absorptive epithelial cells. A highly symmetric hexagonal array of thousands of these ...
  • Molecular Weight Assessment of Proteins in Total Proteome Profiles using 1D-PAGE and LC/MS/MS
    Ahmad, Q Rushdy; Nguyen, Dat H; Wingerd, Mark A; Church, George M; Steffen, Martin A (BioMed Central, 2005-6-8)
    BACKGROUND. The observed molecular weight of a protein on a 1D polyacrylamide gel can provide meaningful insight into its biological function. Differences between a protein's observed molecular weight and that predicted ...
  • MRI and Neuropsychological Correlates of Carbon Monoxide Exposure: A Case Report
    Devine, Sherral A; Kirkley, Shalene M; Palumbo, Carole L; White, Roberta F (National Institute of Environmental Health Sciences, 2002-10)
    A 45-year-old woman experienced long-term, chronic exposure to carbon monoxide in the restaurant kitchen where she was employed as a cook. After returning to the restaurant after 5 days off work, she noticed that her ...
  • MRI Parameters Of Alzheimer's Disease in an Arab Population of Wadi Ara, Israel
    Bowirrat, Abdalla; Reider-Groswasser, Irith I; Oscar-Berman, Marlene; Aizenstein, Orna; Levy, Gad; Korczyn, Amos D (Dove Medical Press, 2005)
    Magnetic resonance imaging (MRI) findings are reported from 15 individuals in an Arab–Israeli community who were diagnosed with Alzheimer's disease (AD). The quantitative parameters that were used for MRI analyses included ...
  • Multifactor-Dimensionality Reduction Versus Family-Based Association Tests in Detecting Susceptibility Loci in Discordant Sib-Pair Studies
    Meng, Yan; Ma, Qianli; Yu, Yi; Farrell, John; Farrer, Lindsay A; Wilcox, Marsha A (BioMed Central, 2005-12-30)
    Complex diseases are generally thought to be under the influence of multiple, and possibly interacting, genes. Many association methods have been developed to identify susceptibility genes assuming a single-gene disease ...
  • A Multilevel Intervention to Promote Colorectal Cancer Screening among Community Health Center Patients: Results of a Pilot Study
    Lasser, Karen E; Murillo, Jennifer; Medlin, Elizabeth; Lisboa, Sandra; Valley-Shah, Lisa; Fletcher, Robert H; Emmons, Karen M; Ayanian, John Z (BioMed Central, 2009-5-29)
    BACKGROUND. Colorectal cancer screening rates are low among poor and disadvantaged patients. Patient navigation has been shown to increase breast and cervical cancer screening rates, but few studies have looked at the ...
  • Multiple Independent Loci at Chromosome 15q25.1 Affect Smoking Quantity: a Meta-Analysis and Comparison with Lung Cancer and COPD
    Saccone, Nancy L.; Culverhouse, Robert C.; Schwantes-An, Tae-Hwi; Cannon, Dale S.; Chen, Xiangning; Cichon, Sven; Giegling, Ina; Han, Shizhong; Han, Younghun; Keskitalo-Vuokko, Kaisu; Kong, Xiangyang; Landi, Maria Teresa; Ma, Jennie Z.; Short, Susan E.; Stephens, Sarah H.; Stevens, Victoria L.; Sun, Lingwei; Wang, Yufei; Wenzlaff, Angela S.; Aggen, Steven H.; Breslau, Naomi; Broderick, Peter; Chatterjee, Nilanjan; Chen, Jingchun; Heath, Andrew C.; Heliövaara, Markku; Hoft, Nicole R.; Hunter, David J.; Jensen, Majken K.; Martin, Nicholas G.; Montgomery, Grant W.; Niu, Tianhua; Payne, Thomas J.; Peltonen, Leena; Pergadia, Michele L.; Rice, John P.; Sherva, Richard; Spitz, Margaret R.; Sun, Juzhong; Wang, Jen C.; Weiss, Robert B.; Wheeler, William; Witt, Stephanie H.; Yang, Bao-Zhu; Caporaso, Neil E.; Ehringer, Marissa A.; Eisen, Tim; Gapstur, Susan M.; Gelernter, Joel; Houlston, Richard; Kaprio, Jaakko; Kendler, Kenneth S.; Kraft, Peter; Leppert, Mark F.; Li, Ming D.; Madden, Pamela A. F.; Nöthen, Markus M.; Pillai, Sreekumar; Rietschel, Marcella; Rujescu, Dan; Schwartz, Ann; Amos, Christopher I.; Bierut, Laura J. (Public Library of Science, 2010-8-5)
    Recently, genetic association findings for nicotine dependence, smoking behavior, and smoking-related diseases converged to implicate the chromosome 15q25.1 region, which includes the CHRNA5-CHRNA3-CHRNB4 cholinergic ...
  • MURC/Cavin-4 and Cavin Family Members Form Tissue-Specific Caveolar Complexes
    Bastiani, Michele; Liu, Libin; Hill, Michelle M.; Jedrychowski, Mark P.; Nixon, Susan J.; Lo, Harriet P.; Abankwa, Daniel; Luetterforst, Robert; Fernandez-Rojo, Manuel; Breen, Michael R.; Gygi, Steven P.; Vinten, Jorgen; Walser, Piers J.; North, Kathryn N.; Hancock, John F.; Pilch, Paul F.; Parton, Robert G. (The Rockefeller University Press, 2009-06-22)
    Polymerase I and transcript release factor (PTRF)/Cavin is a cytoplasmic protein whose expression is obligatory for caveola formation. Using biochemistry and fluorescence resonance energy transfer–based approaches, we now ...
  • Mutations in the Paralogous Human α-globin Genes Yielding Identical Hemoglobin Variants
    Moradkhani, Kamran; Préhu, Claude; Old, John; Henderson, Shirley; Balamitsa, Vera; Luo, Hong-Yuan; Poon, Man-Chiu; Chui, David H. K.; Wajcman, Henri; Patrinos, George P. (Springer-Verlag, 2008-10-16)
    The human α-globin genes are paralogues, sharing a high degree of DNA sequence similarity and producing an identical α-globin chain. Over half of the α-globin structural variants reported to date are only characterized at ...
  • National Survey of Patients' Bill of Rights Statutes
    Paasche-Orlow, Michael K.; Jacob, Dan M.; Hochhauser, Mark; Parker, Ruth M. (Springer-Verlag, 2009-2-3)
    BACKGROUND Despite vigorous national debate between 1999–2001 the federal patients' bill of rights (PBOR) was not enacted. However, states have enacted legislation and the Joint Commission defined an accreditation standard ...
  • Natural Variation of the Amino-Terminal Glutamine-Rich Domain in Drosophila Argonaute2 Is Not Associated with Developmental Defects
    Hain, Daniel; Bettencourt, Brian R.; Okamura, Katsutomo; Csorba, Tibor; Meyer, Wibke; Jin, Zhigang; Biggerstaff, Jason; Siomi, Haruhiko; Hutvagner, Gyorgy; Lai, Eric C.; Welte, Michael; Müller, H.-Arno J. (Public Library of Science, 2010-12-17)
    The Drosophila argonaute2 (ago2) gene plays a major role in siRNA mediated RNA silencing pathways. Unlike mammalian Argonaute proteins, the Drosophila protein has an unusual amino-terminal domain made up largely of multiple ...

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