Browsing School of Medicine by Author "Davis, David A."

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Capzb2 Interacts with β-Tubulin to Regulate Growth Cone Morphology and Neurite Outgrowth

Davis, David A.; Wilson, Meredith H.; Giraud, Jodel; Xie, Zhigang; Tseng, Huang-Chun; England, Cheryl; Herscovitz, Haya; Tsai, Li-Huei; Delalle, Ivana (Public Library of Science, 2009-10-6)

An actin regulatory protein unexpectedly also controls microtubule polymerization during the formation and maintenance of cellular outgrowths in neurons. Capping protein (CP) is a heterodimer that regulates actin assembly ...
Modulators of Cytoskeletal Reorganization in CA1 Hippocampal Neurons Show Increased Expression in Patients at Mid-Stage Alzheimer's Disease

Kao, Patricia F.; Davis, David A.; Banigan, Meredith G.; Vanderburg, Charles R.; Seshadri, Sudha; Delalle, Ivana (Public Library of Science, 2010-10-13)

During the progression of Alzheimer's disease (AD), hippocampal neurons undergo cytoskeletal reorganization, resulting in degenerative as well as regenerative changes. As neurofibrillary tangles form and dystrophic neurites ...

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