Browsing Clinical Science by Subject "Aging"


Browsing Clinical Science by Subject "Aging"

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  • Wright, Robert O.; Schwartz, Joel; Wright, Rosalind J.; Bollati, Valentina; Tarantini, Letizia; Park, Sung Kyun; Hu, Howard; Sparrow, David; Vokonas, Pantel; Baccarelli, Andrea (National Institute of Environmental Health Sciences, 2010-06)
    BACKGROUND. DNA methylation is an epigenetic mark that regulates gene expression. Changes in DNA methylation within white blood cells may result from cumulative exposure to environmental metals such as lead. Bone lead, a ...
  • Holt, Anna EM; Albert, Martin L (Dove Medical Press, 2006)
    Assessments and clinical understanding of late-onset delusions in the elderly are inconsistent and often incomplete. In this review, we consider the prevalence, neurobehavioral features, and neuroanatomic correlations of ...
  • Perlstein, Todd; Weuve, Jennifer; Schwartz, Joel; Sparrow, David; Wright, Robert; Litonjua, Augusto; Nie, Huiling; Hu, Howard (National Institute of Environmental Health Sciences, 2007-12)
    BACKGROUND. Pulse pressure increases with age in industrialized societies as a manifestation of arterial stiffening. Lead accumulates in the vasculature and is associated with vascular oxidative stress, which can promote ...
  • Arora, Manish; Weuve, Jennifer; Weisskopf, Marc G.; Sparrow, David; Nie, Huiling; Garcia, Raul I.; Hu, Howard (National Institute of Environmental Health Sciences, 2009-10)
    BACKGROUND. Individuals previously exposed to lead remain at risk because of endogenous release of lead stored in their skeletal compartments. However, it is not known if long-term cumulative lead exposure is a risk factor ...
  • Peters, Junenette L.; Weisskopf, Marc G.; Spiro, Avron; Schwartz, Joel; Sparrow, David; Nie, Huiling; Hu, Howard; Wright, Robert O.; Wright, Rosalind J. (National Institute of Environmental Health Sciences, 2010-04)
    BACKGROUND. Low-level exposure to lead and to chronic stress may independently influence cognition. However, the modifying potential of psychosocial stress on the neurotoxicity of lead and their combined relationship to ...

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