Burroughs, A Maxwell; Balaji, S; Iyer, Lakshminarayan M; Aravind, L(BioMed Central, 2007-1-24)
BACKGROUND. Domains containing the β-grasp fold are utilized in a great diversity of physiological functions but their role, if any, in soluble or small molecule ligand recognition is poorly studied. RESULTS. Using sensitive ...
Iyer, Lakshminarayan M; Burroughs, A Maxwell; Aravind, L(BioMed Central, 2006-07-19)
A systematic analysis of prokaryotic ubiquitin-related beta-grasp fold proteins provides new insights into the Ubiquitin family functional history. BACKGROUND. Ubiquitin (Ub)-mediated signaling is one of the hallmarks of ...
Burroughs, A Maxwell; Balaji, S; Iyer, Lakshminarayan M; Aravind, L(BioMed Central, 2007-7-2)
BACKGROUND. The β-grasp fold (β-GF), prototyped by ubiquitin (UB), has been recruited for a strikingly diverse range of biochemical functions. These functions include providing a scaffold for different enzymatic active ...
