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The Boston University Institutional Repository contains documents and publications authored or co-authored by BU faculty, students, and staff.
OpenBU is an open access repository, which means that the full text of the work deposited here is freely accessible to the world via the web. Access is restricted only in unavoidable instances, for example where publisher copyright restrictions prevail. However over 90% of scholarly publishers worldwide now allow some version of the documents they publish to be made available in a repository such as this.
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Recently Added
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A tool for the in vivo gating of gene expression in neurons using the co-occurrence of neural activity and light
(2020)Advancements in genetically based technologies have begun to allow us to better understand the relationships between underlying neural activity and the patterns of measurable behavior that can be reproducibly studied in ... -
The mitochondrial transporter ABCB10 protects against oxidative stress in cardiac myocytes
(2020)Oxidative stress and mitochondrial dysfunction have major roles in the pathophysiology of cardiovascular disease. Mitochondria are the predominant source of energy production in the heart. Mitochondrial dysfunction decreases ... -
Defining cellular and molecular mechanisms of hereditary transthyretin amyloidosis
(2020)Hereditary transthyretin amyloidosis (ATTR amyloidosis) is a multi-system protein folding disorder that results from >100 described mutations in the transthyretin (TTR) gene. In the disease, non-natively folded TTR, ... -
The role of proteotoxicity and cross-organelle stress response in drug-induced acute kidney injury
(2022)Nephrotoxicity is a dose-limiting side effect of gentamicin that accounts for a significant portion of clinical acute kidney injury (AKI). The mechanism of gentamicin-induced nephrotoxicity is uncertain and effective ... -
The breakdown of neural function under anesthesia
(2020)Anesthetics have been used for nearly two centuries, and have proved to be one of the most important tools in surgical interventions, but their methods of action remain mysterious. Previous research has focused on high-level, ... -
Boundary encounters: field experiences in undergraduate music teacher preparation through the lens of communities of practice
(2020)Most research in music education using the Communities of Practice (CoP) framework (Wenger, 1998) has focused on analyzing the creation or existence of a CoP. In contrast, this study used the CoP framework as a means to ... -
The role of ATP binding cassette A3 (ABCA3) in health and disease using pluripotent stem cell-derived type II alveolar epithelial cells
(2022)The most common causes of childhood interstitial lung disease (chILD) are autosomal recessive mutations in the gene encoding ATP Binding Cassette A3 (ABCA3) protein, a lamellar body (LB) associated lipid transporter ... -
Renal mechanisms contributing to blood pressure and the development of salt-sensitive hypertension
(2020)High blood pressure or hypertension is a major public health issue that affects more than 50% of adults in the United States. Hypertension is the leading risk factor for multiple cardiovascular events including stroke and ... -
The effect of real time and accelerated aging on the physical and mechanical properties of YTTRIA partially stabilized zirconia
(2020)OBJECTIVES: To evaluate accelerated and real time aging effect on microstructure and mechanical properties of different types of zirconia’s with various surface treatments. METHODS: In this in-vitro study 830 discs were ... -
A research strategy for analyzing the colonial state in Africa
(Boston University, African Studies Center, 1987)This paper presents a research strategy which can usefully be employed to advance the systematic analysis and understanding of the colonial state in Africa. The proposed research strategy is guided by the analytical concerns ...
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