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URI: http://hdl.handle.net/2144/1000

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  • Season, but not symbiont state, drives microbiome structure in the temperate coral Astrangia poculata 

    Sharp, Koty H.; Pratte, Zoe A.; Kerwin, Allison H.; Rotjan, Randi D.; Stewart, Frank J. (2017-12)
    BACKGROUND: Understanding the associations among corals, their photosynthetic zooxanthella symbionts (Symbiodinium), and coral-associated prokaryotic microbiomes is critical for predicting the fidelity and strength of coral ...
  • Temperature and symbiosis affect lesion recovery in experimentally wounded, facultatively symbiotic temperate corals 

    Burmester, E.M.; Finnerty, J.R.; Kaufman, L.; Rotjan, R.D. (Inter-Research, 2017-04-27)
    The health of most reef-building corals depends upon an intracellular symbiosis with photosynthetic dinoflagellates of the genus Symbiodinium that is acutely sensitive to increasing ocean temperatures. However, distinguishing ...
  • Ecological Impacts of the 2015/16 El Niño in the Central Equatorial Pacific 

    Brainard, Russell E.; Oliver, Thomas; McPhaden, Michael J.; Cohen, Anne; Venegas, Roberto; Heenan, Adel; Vargas-Angel, Bernardo; Rotjan, Randi; Mangubhai, Sangeeta; Flint, Elizabeth; Hunter, Susan A. (American Meteorological Society (AMS), 2018-01-01)
  • PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes 

    Soto-Feliciano, Yadira M.; Bartlebaugh, Jordan M.E.; Liu, Yunpeng; Sánchez-Rivera, Francisco J.; Bhutkar, Arjun; Weintraub, Abraham S.; Buenrostro, Jason D.; Cheng, Christine S.; Regev, Aviv; Jacks, Tyler E.; Young, Richard A.; Hemann, Michael T. (2017-05-15)
    Developmental and lineage plasticity have been observed in numerous malignancies and have been correlated with tumor progression and drug resistance. However, little is known about the molecular mechanisms that enable such ...
  • RNA-Seq identifies SPGs as a ventral skeletal patterning cue in sea urchins 

    Piacentino, Michael L.; Zuch, Daniel T.; Fishman, Julie; Rose, Sviatlana; Speranza, Emily E.; Li, Christy; Yu, Jia; Chung, Oliver; Ramachandran, Janani; Ferrell, Patrick; Patel, Vijeta; Reyna, Arlene; Hameeduddin, Hajerah; Chaves, James; Hewitt, Finnegan B.; Bardot, Evan; Lee, David; Core, Amanda B.; Hogan, John D.; Keenan, Jessica L; Luo, Lingqi; Coulombe-Huntington, Jasmin; Blute, Todd A; Oleinik, Ekaterina; Ibn-Salem, Jonas; Poustka, Albert J.; Bradham, Cynthia A. (2016-02-15)
    The sea urchin larval skeleton offers a simple model for formation of developmental patterns. The calcium carbonate skeleton is secreted by primary mesenchyme cells (PMCs) in response to largely unknown patterning cues ...
  • Olfactory receptor accessory proteins play crucial roles in receptor function and gene choice 

    Sharma, Ruchira; Ishimaru, Yoshiro; Davison, Ian; Ikegami, Kentaro; Chien, Ming-Shan; You, Helena; Chi, Quiyi; Kubota, Momoka; Yohda, Masafumi; Ehlers, Michael; Matsunami, Hiroaki
    Each of the olfactory sensory neurons (OSNs) chooses to express a single G protein-coupled olfactory receptor (OR) from a pool of hundreds. Here, we show the receptor transporting protein (RTP) family members play a dual ...
  • Neural mechanisms of social learning in the female mouse 

    Gao, Yuan; Budlong, Carl; Durlacher, Emily; Davison, Ian G.
    Social interactions are often powerful drivers of learning. In female mice, mating creates a long-lasting sensory memory for the pheromones of the stud male that alters neuroendocrine responses to his chemosignals for many ...
  • Survey of variation in human transcription factors reveals prevalent DNA binding changes 

    Barrera, Luis A.; Vedenko, Anastasia; Kurland, Jesse V.; Rogers, Julia M.; Gisselbrecht, Stephen S.; Rossin, Elizabeth J.; Woodard, Jaie; Mariani, Luca; Kock, Kian Hong; Inukai, Sachi; Siggers, Trevor; Shokri, Leila; Gordan, Raluxa; Sahni, Nidhi; Cotsapas, Chris; Hao, Tong; Yi, Song; Kellis, Manolis; Daly, Mark J.; Vidal, Marc; Hill, David E.; Bulyk, Martha L. (2016-03-25)
    Sequencing of exomes and genomes has revealed abundant genetic variation affecting the coding sequences of human transcription factors (TFs), but the consequences of such variation remain largely unexplored. We developed ...
  • Sea anemone model has a single Toll-like receptor that can function in pathogen detection, NF-κB signal transduction, and development 

    Brennan, Joseph J.; Messerschmidt, Jonathan L.; Williams, Leah M.; Matthews, Bryan J.; Reynoso, Marinaliz; Gilmore, Thomas D.
    In organisms from insects to vertebrates, Toll-like receptors (TLRs) are primary pathogen detectors that activate downstream pathways, specifically those that direct expression of innate immune effector genes. TLRs also ...
  • Depolarization-activated potentiation of the T fiber synapse in the blue crab 

    Lin, J.-W.; Llinas, R. (1993-01)
    The blue crab T fiber synapse, associated with the stretch receptor of the swimming leg, has a nonspiking presynaptic element that mediates tonic transmission. This synapse was isolated and a voltage clamp circuit was used ...

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