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  Eucalyptusdimers A-C, dimeric phloroglucinol phellandrene meroterpenoids from Eucalyptus robusta 

  Qin, Xu-Jie; Feng, Mi-Yan; Liu, Hui; Ni, Wei; Rauwolf, Tyler; Porco, John A.; Yan, Huan; He, Li; Liu, Hai-Yang (AMER CHEMICAL SOC, 2018-08-17)

  Eucalyptusdimers A–C, three dimeric phellandrene-derived meroterpenoids featuring an unprecedented, fused skeleton between two phellandrene and two acylphloroglucinol subunits, along with one biogenetically related ...
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  Evaluating the impact of fluorination on the electro-optical properties of cross-conjugated benzobisoxazoles 

  Chavez, Ramiro; Diodati, Lily; Wheeler, David L.; Shaw, Jessica; Tomlinson, Aimee L.; Jeffries-El, Malika (AMER CHEMICAL SOC, 2019-02-21)

  Six 2,4,6,8-tetrarylbenzo[1,2-d:4,5-d′]bisoxazoles (BBOs) were synthesized: three bearing phenyl substituents at the 2- and 6-positions and three bearing perfluorophenyl groups at those positions. The influence of ...
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  Asymmetric synthesis of griffipavixanthone employing a chiral phosphoric acid-catalyzed cycloaddition 

  Smith, Michael J.; Reichl, Kyle D.; Escobar, Randolph A.; Heavey, Thomas J.; Coker, David F.; Schaus, Scott E.; Porco, John A. (AMER CHEMICAL SOC, 2019-01-09)

  Asymmetric synthesis of the biologically active xanthone dimer griffipavixanthone is reported along with its absolute stereochemistry determination. Synthesis of the natural product is accomplished via dimerization of a ...
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  Small molecule amyloid-beta protein precursor processing modulators lower amyloid-beta peptide levels via cKit signaling 

  Chen, Ci-Di; Zeldich, Ella; Khodr, Christina; Camara, Kaddy; Tung, Tze Yu; Lauder, Emma C.; Mullen, Patrick; Polanco, Taryn J.; Liu, Yen-Yu; Zeldich, Dean; Xia, Weiming; Van Nostrand, William E.; Brown, Lauren E.; Porco, John A.; Abraham, Carmela R. (IOS PRESS, 2019-01-01)

  Alzheimer’s disease (AD) is characterized by the accumulation of neurotoxic amyloid-β (Aβ) peptides consisting of 39-43 amino acids, proteolytically derived fragments of the amyloid-β protein precursor (AβPP), and the ...
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  Isolation and synthesis of novel meroterpenoids from rhodomyrtus tomentosa: investigation of a reactive enetrione intermediate 

  Qin, Xu-Jie; Rauwolf, Tyler J.; Li, Pan-Pan; Liu, Hui; McNeely, James; Hua, Yan; Liu, Hai-Yang; Porco, John A. (2019-03-22)

  Rhodomyrtusials A-C, the first examples of triketone-sesquiterpene meroterpenoids featuring a unique 6/5/5/9/4 fused pentacyclic ring system were isolated from Rhodomyrtus tomentosa, along with several biogenetically-related ...
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  Virtual machines: A new way to teach transferable skills in the advanced undergraduate laboratory 

  Georgiadis, Rosina (2018-07-29)
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  Effects of S1 cleavage on the structure, surface export, and signaling activity of human Notch1 and Notch2 

  Gordon, Wendy R.; Vardar-Ulu, Didem; L'Heureux, Sarah; Ashworth, Todd; Malecki, Michael J.; Sanchez-Irizarry, Cheryll; McArthur, Debbie G.; Histen, Gavin; Mitchell, Jennifer L.; Aster, Jon C.; Blacklow, Stephen C. (PUBLIC LIBRARY SCIENCE, 2009-08-24)

  BACKGROUND: Notch receptors are normally cleaved during maturation by a furin-like protease at an extracellular site termed S1, creating a heterodimer of non-covalently associated subunits. The S1 site lies within a key ...
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  The progestin receptor interactome in the female mouse hypothalamus: interactions with synaptic proteins are isoform specific and ligand dependent 

  Acharya, Kalpana D.; Nettles, Sabin A.; Sellers, Katherine J.; Im, Dana D.; Harling, Moriah; Pattanayak, Cassandra; Vardar-Ulu, Didem; Lichti, Cheryl F.; Huang, Shixia; Edwards, Dean P.; Srivastava, Deepak P.; Denner, Larry; Tetel, Marc J. (2017-09)

  Progestins bind to the progestin receptor (PR) isoforms, PR-A and PR-B, in brain to influence development, female reproduction, anxiety, and stress. Hormone-activated PRs associate with multiple proteins to form functional ...
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  Ensuring a successful transition from being a chemistry student to a professional chemist: redesigning an ‘Introductory Biochemistry Laboratory’ curriculum for chemistry majors with a guided focus on transferable skills 

  Vardar-Ulu, Didem (2018-08-01)
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  Can blended instruction provide a customized biochemistry teaching laboratory experience? 

  Vardar-Ulu, Didem (2018-08-01)

  The interdisciplinary nature of the biochemistry courses, present a unique challenge for the educators, who need to work with students previously trained in different disciplines, and will use their biochemistry training ...

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