CAS: Mathematics & Statistics: Scholarly Papers
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Biophysical assay for tethered signaling reactions reveals tethercontrolled activity for the phosphatase SHP1
(201703)Tethered enzymatic reactions are ubiquitous in signaling networks but are poorly understood. A previously unreported mathematical analysis is established for tethered signaling reactions in surface plasmon resonance (SPR). ... 
Why we (usually) don't have to worry about multiple comparisons
(2012)Applied researchers often find themselves making statistical inferences in settings that would seem to require multiple comparisons adjustments. We challenge the Type I error paradigm that underlies these corrections. ... 
MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in singlecell RNA sequencing data
(20151210)Singlecell transcriptomics reveals gene expression heterogeneity but suffers from stochastic dropout and characteristic bimodal expression distributions in which expression is either strongly nonzero or nondetectable. ... 
Reactive boundary conditions as limits of interaction potentials for Brownian and Langevin dynamics
(SIAM PUBLICATIONS, 20160101) 
Transient rapamycin treatment can increase lifespan and healthspan in middleaged mice
(20160803)The FDA approved drug rapamycin increases lifespan in rodents and delays agerelated dysfunction in rodents and humans. Nevertheless, important questions remain regarding the optimal dose, duration, and mechanisms of action ... 
Uniform asymptotic approximation of diffusion to a small target: Generalized reaction models
(201610)The diffusion of a reactant to a binding target plays a key role in many biological processes. The reaction radius at which the reactant and target may interact is often a small parameter relative to the diameter of the ... 
Hopf algebras for matroids over hyperfields
Recently, M.~Baker and N.~Bowler introduced the notion of matroids over hyperfields as a unifying theory of various generalizations of matroids. In this paper we generalize the notion of minors and direct sums from ordinary ... 
Quasicoherent sheaves on projective schemes over F_1
(201707)Given a graded monoid A with 1, one can construct a projective monoid scheme MProj(A) analogous to Proj(R) of a graded ring R. This paper is concerned with the study of quasicoherent sheaves on MProj(A), and we prove several ... 
Čech cohomology over 𝔽12
(201709)In this text, we generalize Cech cohomology to sheaves with values in blue Bmodules where B is a blueprint with −1. If X is an object of the underlying site, then the cohomology sets Hl(X,) turn out to be blue Bmodules. ... 
Wakimoto modules for twisted affine lie algebras
(2002)We construct Wakimoto modules for twisted affine Lie algebras, and interpret the construction in terms of vertex algebras and their twisted modules. Using the Wakimoto realization, we prove the KacKazhdan conjecture on ...