URI: http://hdl.handle.net/2144/1010

Recently Added

  • Spectral Domain Optical Coherence Tomography for Quantitative Evaluation of Drusen and Associated Structural Changes in Non-Neovascular Age-Related Macular Degeneration 

    Yi, K.; Mujat, M.; Park, B. H.; Sun, W.; Miller, J. W.; Seddon, J. M.; Young, L. H.; de Boer, J. F.; Chen, T. C. (BMJ Publishing Group, 2008-12-3)
    BACKGROUND/AIMS:. To demonstrate how spectral domain optical coherence tomography (SDOCT) can better evaluate drusen and associated anatomical changes in eyes with non-neovascular age-related macular degeneration (AMD) ...
  • Stepwise Mechanism for Transcription Fidelity 

    Yuzenkova, Yulia; Bochkareva, Aleksandra; Tadigotla, Vasisht R.; Roghanian, Mohammad; Zorov, Savva; Severinov, Konstantin; Zenkin, Nikolay (BioMed Central, 2010-5-7)
    BACKGROUND. Transcription is the first step of gene expression and is characterized by a high fidelity of RNA synthesis. During transcription, the RNA polymerase active centre discriminates against not just non-complementary ...
  • Mitochondrial DNA Haplogroup D4a Is a Marker for Extreme Longevity in Japan 

    Bilal, Erhan; Rabadan, Raul; Alexe, Gabriela; Fuku, Noriyuki; Ueno, Hitomi; Nishigaki, Yutaka; Fujita, Yasunori; Ito, Masafumi; Arai, Yasumichi; Hirose, Nobuyoshi; Ruckenstein, Andrei; Bhanot, Gyan; Tanaka, Masashi (Public Library of Science, 2008-6-11)
    We report results from the analysis of complete mitochondrial DNA (mtDNA) sequences from 112 Japanese semi-supercentenarians (aged above 105 years) combined with previously published data from 96 patients in each of three ...
  • Signatures of Arithmetic Simplicity in Metabolic Network Architecture 

    Riehl, William J.; Krapivsky, Paul L.; Redner, Sidney; Segrè, Daniel (Public Library of Science, 2010-4-1)
    Metabolic networks perform some of the most fundamental functions in living cells, including energy transduction and building block biosynthesis. While these are the best characterized networks in living systems, understanding ...
  • Distribution of Picophytoplankton Communities from Brackish to Hypersaline Waters in a South Australian Coastal Lagoon 

    Schapira, Mathilde; Buscot, Marie-Jeanne; Pollet, Thomas; Leterme, Sophie C; Seuront, Laurent (BioMed Central, 2010-2-24)
    BACKGROUND. Picophytoplankton (i.e. cyanobacteria and pico-eukaryotes) are abundant and ecologically critical components of the autotrophic communities in the pelagic realm. These micro-organisms colonized a variety of ...
  • Prokaryotic Aminopeptidase Activity along a Continuous Salinity Gradient in a Hypersaline Coastal Lagoon (the Coorong, South Australia) 

    Pollet, Thomas; Schapira, Mathilde; Buscot, Marie-Jeanne; Leterme, Sophie C; Mitchell, James G; Seuront, Laurent (BioMed Central, 2010-4-30)
    The distribution and aminopeptidase activity of prokaryotes were investigated along a natural continuous salinity gradient in a hypersaline coastal lagoon, the Coorong, South Australia. The abundance of prokaryotes ...
  • Head & Neck Optical Diagnostics: Vision of the Future of Surgery 

    Upile, Tahwinder; Jerjes, Waseem; Sterenborg, Henricus J. C. M.; El-Naggar, Adel K.; Sandison, Ann; Witjes, Max J. H.; Biel, Merrill A.; Bigio, Irving; Wong, Brian J. F.; Gillenwater, Ann; MacRobert, Alexander J.; Robinson, Dominic J.; Betz, Christian S.; Stepp, Herbert; Bolotine, Lina; McKenzie, Gordon; Mosse, Charles Alexander; Barr, Hugh; Chen, Zhongping; Berg, Kristian; D'Cruz, Anil K.; Stone, Nicholas; Kendall, Catherine; Fisher, Sheila; Leunig, Andreas; Olivo, Malini; Richards-Kortum, Rebecca; Soo, Khee Chee; Bagnato, Vanderlei; Choo-Smith, Lin-Ping; Svanberg, Katarina; Tan, I. Bing; Wilson, Brian C.; Wolfsen, Herbert; Yodh, Arjun G.; Hopper, Colin (BioMed Central, 2009-07-13)
    Review paper and Proceedings of the Inaugural Meeting of the Head and Neck Optical Diagnostics Society (HNODS) on March 14th 2009 at University College London. The aim of our research must be to provide breakthrough ...
  • Exponential sensitivity of noise-driven switching in genetic networks 

    Mehta, Pankaj; Mukhopadhyay, Ranjan; Wingreen, Ned S. (Physical Biology, 2008)
    Cells are known to utilize biochemical noise to probabilistically switch between distinct gene expression states. We demonstrate that such noise-driven switching is dominated by tails of probability distributions and is ...