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URI: http://hdl.handle.net/2144/1011

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  • Long-term yogurt consumption and risk of incident hypertension in adults 

    Buendia, Justin R.; Li, Yanping; Hu, Frank B.; Cabral, Howard J.; Bradlee, M. Loring; Quatromoni, Paula A.; Singer, Martha R.; Curhar, Gary C.; Moore, Lynn L. (LIPPINCOTT WILLIAMS & WILKINS, 2018-08-01)
  • Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model 

    Tagge, Chad A.; Fisher, Andrew M.; Minaeva, Olga V.; Gaudreau-Balderrama, Amanda; Moncaster, Juliet A.; Zhang, Xiao-Lei; Wojnarowicz, Mark W.; Casey, Noel; Lu, Haiyan; Kokiko-Cochran, Olga N.; Saman, Sudad; Ericsson, Maria; Onos, Kristen D.; Veksler, Ronel; Senatorov, Vladimir V.; Kondo, Asami; Zhou, Xiao Z.; Miry, Omid; Vose, Linnea R.; Gopaul, Katisha R.; Upreti, Chirag; Nowinski, Christopher J.; Cantu, Robert C.; Alvarez, Victor E.; Hildebrandt, Audrey M.; Franz, Erich S.; Konrad, Janusz; Hamilton, James A.; Hua, Ning; Tripodis, Yorghos; Anderson, Andrew T.; Howell, Gareth R.; Kaufer, Daniela; Hall, Garth F.; Lu, Kun P.; Ransohoff, Richard M.; Cleveland, Robin O.; Kowall, Neil W; Stein, Thor D.; Lamb, Bruce T.; Huber, Bertrand R.; Moss, William C.; Friedman, Alon; Stanton, Patric K.; McKee, Ann C.; Goldstein, Lee E (OXFORD UNIV PRESS, 2018-02-01)
    The mechanisms underpinning concussion, traumatic brain injury, and chronic traumatic encephalopathy, and the relationships between these disorders, are poorly understood. We examined post-mortem brains from teenage athletes ...
  • PleioGRiP: Pleiotropic Genetic Risk Prediction via Bayesian model search and classification 

    Sebastiani, Paola; Hartley, Stephen (2012-11-16)
    The program PleioGRiP performs a genome-wide Bayesian model search to identify SNPs associated with a discrete phenotype, and uses SNPs ranked by Bayes factor to produce nested Bayesian classifiers. These classifiers can ...
  • Handling Linkage Disequilibrium in Qualitative Trait Linkage Analysis Using Dense SNPs: A Two-Step Strategy 

    Cho, Kelly; Dupuis, Josée (BioMed Central, 2009-8-10)
    BACKGROUND. In affected sibling pair linkage analysis, the presence of linkage disequilibrium (LD) has been shown to lead to overestimation of the number of alleles shared identity-by-descent (IBD) among sibling pairs when ...
  • Joint Modeling of Linkage and Association Using Affected Sib-Pair Data 

    Chen, Ming-Huei; Cui, Jing; Guo, Chao-Yu; Cupples, L Adrienne; Van Eerdewegh, Paul; Dupuis, Josée; Yang, Qiong (BioMed Central, 2007-12-18)
    There has been a growing interest in developing strategies for identifying single-nucleotide polymorphisms (SNPs) that explain a linkage signal by joint modeling of linkage and association. We compare several existing ...
  • Incorporating Biological Knowledge in the Search for Gene × Gene Interaction in Genome-Wide Association Studies 

    Manning, Alisa K; Ngwa, Julius Suh; Hendricks, Audrey E; Liu, Ching-Ti; Johnson, Andrew D; Dupuis, Josée; Cupples, L Adrienne (BioMed Central, 2009-12-15)
    We sought to find significant gene × gene interaction in a genome-wide association analysis of rheumatoid arthritis (RA) by performing pair-wise tests of interaction among collections of single-nucleotide polymorphisms ...
  • Genetic Analysis Workshop 16: Strategies for Genome-Wide Association Study Analyses 

    Cupples, L. Adrienne; Beyene, Joseph; Bickeböller, Heike; Daw, E. Warwick; Fallin, M. Daniele; Gauderman, W. James; Ghosh, Saurabh; Goode, Ellen L.; Hauser, Elizabeth R.; Hinrichs, Anthony; Kent, Jack W.; Martin, Lisa J.; Martinez, Maria; Neuman, Rosalind J.; Province, Michael; Szymczak, Silke; Wilcox, Marsha A.; Ziegler, Andreas; MacCluer, Jean W.; Almasy, Laura (BioMed Central, 2009-12-15)
  • Handling Linkage Disequilibrium in Linkage Analysis Using Dense Single-Nucleotide Polymorphisms 

    Cho, Kelly; Yang, Qiong; Dupuis, Josée (BioMed Central, 2007-12-18)
    The presence of linkage disequilibrium violates the underlying assumption of linkage equilibrium in most traditional multipoint linkage approaches. Studies have shown that such violation leads to bias in qualitative trait ...
  • Genetics Analysis Workshop 16 Problem 2: tTe Framingham Heart Study Data 

    Cupples, L. Adrienne; Heard-Costa, Nancy; Lee, Monica; Atwood, Larry D. (BioMed Central, 2009-12-15)
    Genetic Analysis Workshop 16 (GAW16) Problem 2 presented data from the Framingham Heart Study (FHS), an observational, prospective study of risk factors for cardiovascular disease begun in 1948. Data have been collected ...
  • Genome-Wide Association and Linkage Analysis of Quantitative Traits: Comparison pf Likelihood-Ratio Test and Conditional Score Statistic 

    Hendricks, Audrey E; Zhu, Yanyan; Dupuis, Josée (BioMed Central, 2009-12-15)
    Over the past decade, genetic analysis has shifted from linkage studies, which identify broad regions containing putative trait loci, to genome-wide association studies, which detect the association of a marker with a ...

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