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dc.contributor.authorAdams, Richard Augusten_US
dc.date.accessioned2015-07-02T21:02:48Z
dc.date.available2015-07-02T21:02:48Z
dc.date.issued1956
dc.date.submitted1956
dc.identifier.otherb14634946
dc.identifier.urihttps://hdl.handle.net/2144/11580
dc.descriptionThesis (Ph.D)--Boston Universityen_US
dc.description.abstractAn investigation of first-set and second-set skin homografts in hamsters has been made in an attempt to characterize agouti and albino hamsters (Mesocricetus auratus) with respect to their genetic homogeneity. This work represents the first reported experimental investigation of skin homografting in hamsters. Attempts to characterize animals with regard to their genetic similarity or dissimilarity by homografting skin are based on the welldocumented observations that homografts fail experimentally unless made between members of highly inbred strains, or succeed clinically ooly when donor and host are identical twins. The most notable exception to this formulation is the recent communication by Eichwald and Silmser (19.55) that even within inbred strains of mice, homografts of sldn from males to females failed , due probably to the Y-linkage of a histocompatibility locus (Hauschka, 1955; Snell, 1956). Snell points out that the fineness of the homograft response to skin, i.e. the complete dependence of successful grafting on genetic identity, may be used more profitably than tumor transplantation tests to explore the "weaker" histocompatibility loci.[Truncated]en_US
dc.language.isoen_US
dc.publisherBoston Universityen_US
dc.rightsBased on investigation of the BU Libraries' staff, this work is free of known copyright restrictions.en_US
dc.titleOrthotopic Skin Grafting in Albino and Agouti Hamstersen_US
dc.typeThesis/Dissertationen_US
etd.degree.nameDoctor of Philosophyen_US
etd.degree.leveldoctoralen_US
etd.degree.disciplineBiologyen_US
etd.degree.grantorBoston Universityen_US


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