Show simple item record

dc.contributor.authorAtkinson, Wendy Lauraen_US
dc.date.accessioned2015-08-04T15:28:45Z
dc.date.available2015-08-04T15:28:45Z
dc.date.issued2013
dc.date.submitted2013
dc.identifier.other
dc.identifier.urihttps://hdl.handle.net/2144/12049
dc.descriptionThesis (M.A.)--Boston Universityen_US
dc.description.abstractPurpose: To evaluate the diagnostic performance of simultaneous FDG-PET/MR compared to FDG-PET/CT in non-Hodgkin’s and Hodgkin’s lymphoma. Methods: This cross-sectional study included fifteen patients with a confirmed diagnosis of NHL or HL who had completed a clinical FDG-PET/CT and a same day research FDG-PET/MR. SUVmax for FDG-avid lesions were measured for each imaging modality, as well as ADC from FDG-PET/MR. Strength of correlation between variables was measured using the Spearman rank correlation coefficient (rs). The overall radiation exposure dose was also calculated for a clinical FDG-PET/CT and compared to the radiation dose level remaining at time of FDG-PET/MR. Results: Thirty-seven concordant FDG-avid lesions were identified on both PET/CT and PET/MR imaging. SUVmax from FDG-PET/MR versus FDG-PET/CT demonstrated a strongly positive correlation (rs=0.84 (0.71, 0.92); p<0.0001). There was no correlation found between ADCmin and SUVmax from FDG- PET/MR (r=0.35(-0.07, 0.66); p=0.09). The overall radiation exposure from one FDG-PET/CT was 24.07±6.06mSv (range: 17.67-33.84mSv) compared to the decay-corrected radiation dose at FDG-PET/MR (2.87±0.92mSv (range: 1.86- 5.90mSv)). Conclusion: FDG-PET/MR offers a comparable whole body staging examination with an improved radiation safety profile in NHL and HL patients when based on the maximum standardized uptake value.en_US
dc.language.isoen_US
dc.publisherBoston Universityen_US
dc.titleDoes FDG-PET/MR offer a similar diagnostic performance to FDG-PET/CT, and therefore, offer a comparable whole-body staging examination in patients diagnosed with non-Hodgkin's and Hodgkin's lymphoma?en_US
dc.typeThesis/Dissertationen_US
etd.degree.nameMaster of Artsen_US
etd.degree.levelmastersen_US
etd.degree.disciplineMedical Sciencesen_US
etd.degree.grantorBoston Universityen_US


This item appears in the following Collection(s)

Show simple item record