A retrospective analysis to identify characteristics associated with bone fractures observed in patients who undergo the Foker process

Abstract

Introduction: Esophageal atresia (EA), a rare anomaly characterized by a gap within the esophageal tract, causes serious complications in newborn infants. Surgery is the only treatment available to cure EA. This study focuses on Long Gap Esophageal Atresia (LGEA) reconstructive surgery using the Foker process for in vivo growth induction of the esophagus. This process incorporates multiple surgeries that take place over a period of weeks to months. Patients undergoing LGEA surgery may be at greater risk for bone fracture, due to poor nutritional status, administration of certain medications and prolonged periods of immobility. Other risk factors contributing to bone fragility include low birth weight and other congenital anomalies. This study uses a retrospective analysis to determine which variables may contribute to fractures in patients who have undergone the Foker procedure. Objectives: Clinical characteristics (age, gestational age, associated congenital anomalies, total Foker surgical procedures, Foker process duration and total days of administered paralytics) associated with fractures in patients who underwent the Foker procedure were determined. [TRUNCATED]