2014 REU Poster: Quantifying Lipid Contents In Liposomes with Enveloped Plasmonic Nanoparticles

Abstract

Phosphatidylserine(PS) and monosialotetrahexosylganglioside(GM1) are examples of two host-derived lipids in the membrane of enveloped virus particles that are known to contribute to virus attachment, uptake, and ultimately dissemination. We learn the binding infinity of PS and GM1 lipid by using gold nanoparticle (GNP) since it is stable and conductive. Besides, changing concentration of lipid on the virus can control how the virus infective. The performed studies can use identify unknown concentration of lipid.