The chromatophore activating substance in the pituitary gland of the vertebrates
Lavenberg, Leonard Seymour
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￼This paper is concerned with the color changes of the cold blooded vertebrates in which the pigment ceils of the integument are concerned. It was first thought that these pigment cells or chromatophores actually contracted and expanded, amoeba-like, during alterations of tint. Careful studies showed that in the melanophores or black pigment cells, this was not the case. Here the pigment granules migrated within the clear protoplasm of a cell with fixed boundaries. This led to a change in the nomenclature from "expansion and contraction" of the chromatophores to "dispersion and concentration of the pigment" of these cells. The variations in the position of the pigment in these tiny cells account for the color changes which can be noted with the naked eye.
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