A validation of mobile sensing actigraphy devices for generating a biomechanical model of posture
Detheridge, Craig Neal
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Mobile sensing actigraphy was tested and validated as a modality for computing dynamic posturography. Twelve healthy volunteer subjects (6 male) were administered risperidone and assessed for postural stability using a NeuroCom® Balance Master system and BioSensics® mobile sensors at baseline, 2 hours, 6 hours, and 24 hours post-dose. A strong positive correlation was shown between BioSensics and Balance Master systems in a modified Sensory Organization Task, with Pearson’s r = 0.76, p < 0.001 on composite equilibrium scores. Strong to moderate correlations during the same task showed r = 0.48, p < 0.001 to r = 0.74, p < 0.001. Mobile sensing actigraphy may be a viable alternative to force plate posturography in assessing drug-induced postural instability.