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dc.contributor.authorAmiel, Jean-Pierre L.en_US
dc.date.accessioned2017-04-10T13:13:33Z
dc.date.available2017-04-10T13:13:33Z
dc.date.issued1959
dc.date.submitted1959
dc.identifier.otherb14693975
dc.identifier.urihttps://hdl.handle.net/2144/20968
dc.descriptionThesis (M.A.)--Boston Universityen_US
dc.description.abstractDue to the actual high price of hydrazine, this chemical cannot be used in an economical preparation of organic hydrazides. A synthesis of such hydrazides can be envisaged by the reduction of N-nitroamides. The problem is then to find a set of conditions under which no hydrogenolysis of the nitrogen-nitrogen bond occurs. This had been done with N-nitrocarbamates and it was hoped that the results could be extended to N-nitroamides: N-Nitro-N-methylamides were actually used in order to have a more stable N-nitro group. Dimethylation of the hydrazine could be performed either by acid hydrolysis of the addition product obtained with diethyl azodicarboxylate or by heating with pyridinium chloride. After failure to reduce p-N-dinitro-N-methylbenzamide to hydrazine, a new technique was experienced by which the amide was nitrated and reduced directly without isolation of the N-nitroamide. Preliminary results suggested that the electron shifting ability of the R group in molecules of the type R CO-N(NO2)CH3 is very important in their reduction to hydrazine. Several molecules were then reduced with different R. It was found that the yield of hydrazine increases with the electron repelling ability if R. A mechanism involving formation of an unstable platinum hydride is proposed for the reaction. A survery of the addition reactions of azodicarboxylic esters is given with the description of an attempt of "Azo reaction" between diethyl azodicarboxylate and p-N-dinitro-N-methylbenzamide.en_US
dc.language.isoen_US
dc.publisherBoston Universityen_US
dc.rightsBased on investigation of the BU Libraries' staff, this work is free of known copyright restrictions.en_US
dc.titlePreparation of organic hydrazidesen_US
dc.typeThesis/Dissertationen_US
etd.degree.nameMaster of Artsen_US
etd.degree.levelmastersen_US
etd.degree.disciplineScienceen_US
etd.degree.grantorBoston Universityen_US


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