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dc.contributor.authorShepro, David
dc.date.accessioned2017-06-20T19:13:37Z
dc.date.available2017-06-20T19:13:37Z
dc.date.issued1959
dc.date.submitted1959
dc.identifier.otherb14672947
dc.identifier.urihttps://hdl.handle.net/2144/22514
dc.descriptionThesis (Ph.D.)--Boston University
dc.description.abstractThe golden hamster, Mesocricetus auratus, is unique in that it frequently accepts not only homografts but even heterografts of normal and malignant tissues. One of the many theories a tterpting an explanation of this phenomenon, namely that lymphatic tissues that drain the sites of imphntation do not respond in a t;rpicol fashion, motivated this study. Thus, the weight changes ,and the c;'tolof'ical variations of the superficial cervical nodes in response to homologous and heterologous normal and malignant tissue transplants in the cheek pouch of the hamster were studied. The major objectives were: (1) to determine if there be any "defect" in the hamster's lymphatic tissue response to the various transplants; (2) to investigate the effects of the grafts on the large lymphoid cells of the cortex and on the plasma cells of the medulla; and ( 3) to investigate the feasibility of employing the histological picture of a regional node draining the site of a tumor heterotransplant as a base line for anti-tumor studies during the cortisone conditioning. [TRUNCATED]
dc.language.isoen_US
dc.publisherBoston University
dc.rightsBased on investigation of the BU Libraries' staff, this work is free of known copyright restrictions.
dc.subjectMesocricetus auratus
dc.subjectLymph nodes
dc.subjectTumors
dc.subjectHamsters
dc.titleRegional lymph node response to homologons and heterologous transplants of tumor and normal tissues in the cheek pouch of the hamster
dc.typeThesis/Dissertation
etd.degree.nameDoctor of Philosophy
etd.degree.leveldoctoral
etd.degree.disciplineBiology
etd.degree.grantorBoston University


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