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dc.contributor.authorAlSulaiman, Wafaen_US
dc.date.accessioned2017-09-08T18:19:36Z
dc.date.available2017-09-08T18:19:36Z
dc.date.issued2017
dc.identifier.urihttps://hdl.handle.net/2144/23752
dc.description.abstractNumerous analyses have explored the role of statins in reducing stroke incidence, reducing cerebral ischemia in hypercholesterolemic patients, and preventing ischemic stroke. This paper aims to assess the effect of statins in lowering the risk of stroke and preventing cerebral ischemia in patients with hypercholesterolemia. To achieve this objective, the literature was reviewed, randomized control tests were analyzed, and a systematic review was performed. The risk of developing cerebral ischemia was found to be reduced in hypercholesterolemic patients and patients with a history of cerebrovascular disease. However, it is unknown whether this reduction in incidence is a result of the drug, which reduces low-density lipoprotein levels in the blood, or to statins’ pleotropic effects on the vascular endothelium. Since their discovery, statins have proven to be beneficial in controlling cholesterol blood levels. Moreover, statins have been shown to have pleotropic effects after a certain period of use, one of which is lowering ischemic stroke incidence in hypercholesterolemic patients. Most recently, statins have been found to lower systolic blood pressure. It is not yet clear whether it has a significant effect on mortality or whether or not it is linked to statins.en_US
dc.language.isoen_US
dc.subjectMedicineen_US
dc.titleAssessing the effect of statins in lowering the risk of stroke and preventing cerebral ischemia in patients with hypercholesterolemiaen_US
dc.typeThesis/Dissertationen_US
dc.date.updated2017-07-12T19:17:55Z
etd.degree.nameMaster of Scienceen_US
etd.degree.levelmastersen_US
etd.degree.disciplineMedical Sciencesen_US
etd.degree.grantorBoston Universityen_US


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