Metabolism of testosterone by tissue enzymes
Simpson, Norma J.
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From a series of in vitro incubations with human skin the existence of an enzyme system which metabolizes testosterone to [triangle]^4-androstene-3, 17-dione and "polar compounds" has been established. Several enzyme systems are felt to be active in testosterone breakdown by human skin; some of these from "polar compounds", one of them forms [triangle]^4-androstene-3,17-dione, while others form additional unknown ketonic compounds. These skin enzymes were found to vary quantitatively among different subjects. [TRUNCATED]
Thesis (M.A.)--Boston University