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dc.contributor.authorLong, J.en_US
dc.contributor.authorZhang, Y.en_US
dc.contributor.authorBrusic, V.en_US
dc.contributor.authorChitkushev, L.en_US
dc.contributor.authorZhang, G.en_US
dc.coverage.spatialBoston, USAen_US
dc.date.accessioned2017-11-01T17:54:01Z
dc.date.available2017-11-01T17:54:01Z
dc.date.issued2017-08-23
dc.identifier.citationJ. Long, Y. Zhang, V. Brusic, L. Chitkushev, G. Zhang. 2017. "Antidote application: an educational system for treatment of common toxin overdose." ACM-BCB 2017. Boston, USA, 2017-08-20 - 2017-08-23
dc.identifier.urihttps://hdl.handle.net/2144/24686
dc.description.abstractPoisonings account for almost 1% of emergency room visits each year. Time is a critical factor in dealing with a toxicologic emergency. Delay in dispensing the first antidote dose can lead to life-threatening sequelae. Current toxicological resources that support treatment decisions are broad in scope, time-consuming to read, or at times unavailable. Our review of current toxicological resources revealed a gap in their ability to provide expedient calculations and recommendations about appropriate course of treatment. To bridge the gap, we developed the Antidote Application (AA), a computational system that automatically provides patient-specific antidote treatment recommendations and individualized dose calculations. We implemented 27 algorithms that describe FDA (the US Food and Drug Administration) approved use and evidence-based practices found in primary literature for the treatment of common toxin exposure. The AA covers 29 antidotes recommended by Poison Control and toxicology experts, 19 poison classes and 31 poisons, which represent over 200 toxic entities. To the best of our knowledge, the AA is the first educational decision support system in toxicology that provides patient-specific treatment recommendations and drug dose calculations. The AA is publicly available at http://projects.met- hilab.org/antidote/.en_US
dc.language.isoen_US
dc.rights© 2017 Copyright is held by the owner/author(s). Publication rights licensed to ACM.en_US
dc.subjectMedical informaticsen_US
dc.subjectPoison control centersen_US
dc.subjectToxicologyen_US
dc.subjectToxicityen_US
dc.subjectDecision supporten_US
dc.titleAntidote application: an educational system for treatment of common toxin overdoseen_US
dc.typeConference materialsen_US
pubs.elements-sourcemanual-entryen_US
pubs.notesEmbargo: Not knownen_US
pubs.organisational-groupBoston Universityen_US
pubs.organisational-groupBoston University, Metropolitan Collegeen_US
pubs.publication-statusPublisheden_US
dc.identifier.orcid0000-0001-6010-490X (Zhang, G)


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