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dc.contributor.authorWang, Puen_US
dc.contributor.authorSlipchenko, Mikhail N.en_US
dc.contributor.authorMitchell, Jamesen_US
dc.contributor.authorYang, Chenen_US
dc.contributor.authorPotma, Eric O.en_US
dc.contributor.authorXu, Xianfanen_US
dc.contributor.authorCheng, Ji-Xinen_US
dc.coverage.spatialEnglanden_US
dc.date.accessioned2018-02-13T15:00:40Z
dc.date.available2018-02-13T15:00:40Z
dc.date.issued2013
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/24436725
dc.identifier.citationPu Wang, Mikhail N Slipchenko, James Mitchell, Chen Yang, Eric O Potma, Xianfan Xu, Ji-Xin Cheng. 2013. "Far-field Imaging of Non-fluorescent Species with Sub-diffraction Resolution.." Nat Photonics, Volume 7, pp. 449 - 453.
dc.identifier.issn1749-4885
dc.identifier.urihttps://hdl.handle.net/2144/26998
dc.description.abstractSuper-resolution optical microscopy is opening a new window to unveil the unseen details on the nanoscopic scale. Current far-field super-resolution techniques rely on fluorescence as the read-out1-5. Here, we demonstrate a scheme for breaking the diffraction limit in far-field imaging of non-fluorescent species by using spatially controlled saturation of electronic absorption. Our method is based on a pump-probe process where a modulated pump field perturbs the charge-carrier density in a sample, thus modulating the transmission of a probe field. A doughnut shape laser beam is then added to transiently saturate the electronic transition in the periphery of the focal volume, thus the induced modulation in the sequential probe pulse only occurs at the focal center. By raster scanning the three collinearly aligned beams, high-speed sub-diffraction-limited imaging of graphite nano-platelets was performed. This technique potentially enables super-resolution imaging of nano-materials and non-fluorescent chromophores, which may remain out of reach for fluorescence-based methods.en_US
dc.description.sponsorshipR21 EB015901 - NIBIB NIH HHS; R21 GM104681 - NIGMS NIH HHS; R21 RR032384 - NCRR NIH HHSen_US
dc.format.extent449 - 453en_US
dc.languageeng
dc.relation.ispartofNat Photonics
dc.subjectScience & technologyen_US
dc.subjectPhysical sciencesen_US
dc.subjectOpticsen_US
dc.subjectPhysics, applieden_US
dc.subjectPhysicsen_US
dc.subjectStimulated emissionen_US
dc.subjectSaturable absorberen_US
dc.subjectOptical absorptionen_US
dc.subjectCarrier dynamicsen_US
dc.subjectMicroscopyen_US
dc.subjectGrapheneen_US
dc.subjectBiocompatibilityen_US
dc.subjectNanoparticlesen_US
dc.subjectNanoscopyen_US
dc.subjectMathematical sciencesen_US
dc.subjectOptoelectronics & photonicsen_US
dc.titleFar-field imaging of non-fluorescent species with sub-diffraction resolutionen_US
dc.typeArticleen_US
dc.identifier.doi10.1038/nphoton.2013.97
pubs.elements-sourcepubmeden_US
pubs.notesEmbargo: Not knownen_US
pubs.organisational-groupBoston Universityen_US
pubs.organisational-groupBoston University, College of Engineeringen_US
pubs.organisational-groupBoston University, College of Engineering, Department of Electrical & Computer Engineeringen_US
pubs.publication-statusPublisheden_US
dc.identifier.orcid0000-0001-9454-847X (Yang, Chen)
dc.identifier.orcid0000-0002-5607-6683 (Cheng, Ji-Xin)


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