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dc.contributor.authorMorello, Josephine Annaen_US
dc.date.accessioned2018-04-05T17:19:30Z
dc.date.available2018-04-05T17:19:30Z
dc.date.issued1962
dc.date.submitted1962
dc.identifier.otherb14677908
dc.identifier.urihttps://hdl.handle.net/2144/28100
dc.descriptionThesis (Ph.D.)--Boston Universityen_US
dc.description.abstractThe investigation of the fate of bacteria which are normally intracellular parasites has interested workers for many years. or special interest have been the roles played by phagocytic cells and immune sera in the resistance of animals against infections produced by these organisms. The research whose results are presented here was undertaken to study the role of phagocytic cells (macrophages) in immunity to Salmonella typhosa. Experiments were performed with macrophages isolated from the peritoneal cavities of mice. Cultures of these cells were prepared, and infected with virulent and avirulent strains of S. typhosa and Salmonella typhimurium. Streptomycin was added to some cultures after the period of phagocytosis to prevent extracellular growth of the bacteria. The phagocytic and bactericidal abilities of the macrophages were determined by comparisons of viable counts of organisms released from the cells and the number of intracellular bacteria on stained cover slip preparations [TRUNCATED]en_US
dc.language.isoen_US
dc.publisherBoston Universityen_US
dc.rightsBased on investigation of the BU Libraries' staff, this work is free of known copyright restrictions.en_US
dc.subjectSalmonellaen_US
dc.subjectStreptomycinen_US
dc.titleInteraction of salmonella with phagocytes in vitroen_US
dc.typeThesis/Dissertationen_US
etd.degree.nameDoctor of Philosophyen_US
etd.degree.leveldoctoralen_US
etd.degree.disciplinePhilosophyen_US
etd.degree.grantorBoston Universityen_US


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